Evaluation of the Histopathologic Reports of Oral Lesions in Razi Laboratory in Rasht in 2014-2018

Background: Oral lesions can affect people’s quality of life by interfering with chewing, swallowing, and speech. These lesions may originate from epithelial or mesenchymal tissues. Malignant oral lesions can be life-threatening. Epidemiological data of oral lesions in Iran is limited. Objective: Th...

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Main Authors: Narges Alizadeh, Maryam Rabiei, Amirreza Sayyar, Rana Rafiei, Nooshin Zaresharifi, Habib Eslami
Format: Article
Language:fas
Published: Guilan University of Medical Sciences 2023-04-01
Series:مجله دانشگاه علوم پزشکی گیلان
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Online Access:http://journal.gums.ac.ir/article-1-2557-en.pdf
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author Narges Alizadeh
Maryam Rabiei
Amirreza Sayyar
Rana Rafiei
Nooshin Zaresharifi
Habib Eslami
author_facet Narges Alizadeh
Maryam Rabiei
Amirreza Sayyar
Rana Rafiei
Nooshin Zaresharifi
Habib Eslami
author_sort Narges Alizadeh
collection DOAJ
description Background: Oral lesions can affect people’s quality of life by interfering with chewing, swallowing, and speech. These lesions may originate from epithelial or mesenchymal tissues. Malignant oral lesions can be life-threatening. Epidemiological data of oral lesions in Iran is limited. Objective: This study aims to investigate the frequency of oral lesions in Rasht, Iran. Methods: In this cross-sectional study, histopathologic data of oral lesions reported by Razi laboratory in Rasht from 2015 to 2019 were evaluated. The data collected: Patients’ age and sex, histopathologic findings, and location, type and origin of lesions. Non-specific diagnoses and dental and bone lesions were excluded. Results: A total of 259 pathologic reports were included. The mean age patients was 52.09±19 years, and 40.2% were male. Oral lesions in patients aged <40 years were mainly benign (64.2%), whereas half of lesions in patients ≥70 years were mostly malignant. Tongue was the most common location of the lesions (34.7%) and the main location for malignant lesions (46.7%). Benign lesions were significantly higher in females whereas malignant lesions were significantly higher in males (P=0.011). Epithelial tissues were the most common site of origin (49%) and salivary glands were the least common site of origin (11.6%) for oral lesions. Conclusion: Malignant oral lesions are more common in Iranian men aged >70 years, where the tongue is the most common site of involvement and epithelial tissue is the main site of origin.
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publisher Guilan University of Medical Sciences
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spelling doaj-art-0795c7f3f7294ea79abeb66c6cb205582025-08-20T03:04:59ZfasGuilan University of Medical Sciencesمجله دانشگاه علوم پزشکی گیلان2008-40482008-40562023-04-013213039Evaluation of the Histopathologic Reports of Oral Lesions in Razi Laboratory in Rasht in 2014-2018Narges Alizadeh0Maryam Rabiei1Amirreza Sayyar2Rana Rafiei3Nooshin Zaresharifi4Habib Eslami5 Department of Dermatology, Skin Research Center, School of Medicine, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran. Department of Oral and Maxillofacial Medicine, Dental Sciences Research Center, School of Dentistry, Guilan University of Medical Sciences, Rasht, Iran. Department of Dermatology, Skin Research Center, School of Medicine, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran. Department of Dermatology, Skin Research Center, School of Medicine, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran. Department of Pathology, School of Medicine, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Department of Dermatology, Skin Research Center, School of Medicine, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran. Background: Oral lesions can affect people’s quality of life by interfering with chewing, swallowing, and speech. These lesions may originate from epithelial or mesenchymal tissues. Malignant oral lesions can be life-threatening. Epidemiological data of oral lesions in Iran is limited. Objective: This study aims to investigate the frequency of oral lesions in Rasht, Iran. Methods: In this cross-sectional study, histopathologic data of oral lesions reported by Razi laboratory in Rasht from 2015 to 2019 were evaluated. The data collected: Patients’ age and sex, histopathologic findings, and location, type and origin of lesions. Non-specific diagnoses and dental and bone lesions were excluded. Results: A total of 259 pathologic reports were included. The mean age patients was 52.09±19 years, and 40.2% were male. Oral lesions in patients aged <40 years were mainly benign (64.2%), whereas half of lesions in patients ≥70 years were mostly malignant. Tongue was the most common location of the lesions (34.7%) and the main location for malignant lesions (46.7%). Benign lesions were significantly higher in females whereas malignant lesions were significantly higher in males (P=0.011). Epithelial tissues were the most common site of origin (49%) and salivary glands were the least common site of origin (11.6%) for oral lesions. Conclusion: Malignant oral lesions are more common in Iranian men aged >70 years, where the tongue is the most common site of involvement and epithelial tissue is the main site of origin.http://journal.gums.ac.ir/article-1-2557-en.pdfpathologyoral cavitymucosa
spellingShingle Narges Alizadeh
Maryam Rabiei
Amirreza Sayyar
Rana Rafiei
Nooshin Zaresharifi
Habib Eslami
Evaluation of the Histopathologic Reports of Oral Lesions in Razi Laboratory in Rasht in 2014-2018
مجله دانشگاه علوم پزشکی گیلان
pathology
oral cavity
mucosa
title Evaluation of the Histopathologic Reports of Oral Lesions in Razi Laboratory in Rasht in 2014-2018
title_full Evaluation of the Histopathologic Reports of Oral Lesions in Razi Laboratory in Rasht in 2014-2018
title_fullStr Evaluation of the Histopathologic Reports of Oral Lesions in Razi Laboratory in Rasht in 2014-2018
title_full_unstemmed Evaluation of the Histopathologic Reports of Oral Lesions in Razi Laboratory in Rasht in 2014-2018
title_short Evaluation of the Histopathologic Reports of Oral Lesions in Razi Laboratory in Rasht in 2014-2018
title_sort evaluation of the histopathologic reports of oral lesions in razi laboratory in rasht in 2014 2018
topic pathology
oral cavity
mucosa
url http://journal.gums.ac.ir/article-1-2557-en.pdf
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