A Novel Quinoline Inhibitor of the Canonical NF-κB Transcription Factor Pathway

A Novel Quinoline Inhibitor of the Canonical NF-κB Transcription Factor Pathway

The NF-κB family of transcription factors is a master regulator of cellular responses during inflammation, and its dysregulation has been linked to chronic inflammatory diseases, such as inflammatory bowel disease. It is therefore of vital importance to design and test new effective NF-κB inhibitors...

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Bibliographic Details
Main Authors: Panagiotis Ntavaroukas, Konstantinos Michail, Rafaela Tsiakalidou, Eleni Stampouloglou, Katerina Tsiggene, Dimitrios Komiotis, Nikitas Georgiou, Thomas Mavromoustakos, Stella Manta, Danielle Aje, Panagiotis Michael, Barry J. Campbell, Stamatia Papoutsopoulou
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biology
Subjects:
NF-κB
inflammation
quinoline
transcription
Online Access:https://www.mdpi.com/2079-7737/13/11/910
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