Endoscopic combined “transseptal/transnasal” approach for pituitary adenoma: reconstruction of skull base using pedicled nasoseptal flap in 91 consecutive cases

Objective The purpose of this study was to describe the endoscopic combined “transseptal/transnasal” approach with a pedicled nasoseptal flap for pituitary adenoma and skull base reconstruction, especially with respect to cerebrospinal fluid (CSF) fistula.Method Ninety-one consecutive patients with...

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Main Authors: Yasunori Fujimoto, Leonardo Balsalobre, Fábio P. Santos, Eduardo Vellutini, Aldo C. Stamm
Format: Article
Language:English
Published: Thieme Revinter Publicações 2015-07-01
Series:Arquivos de Neuro-Psiquiatria
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000700611&lng=en&tlng=en
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author Yasunori Fujimoto
Leonardo Balsalobre
Fábio P. Santos
Eduardo Vellutini
Aldo C. Stamm
author_facet Yasunori Fujimoto
Leonardo Balsalobre
Fábio P. Santos
Eduardo Vellutini
Aldo C. Stamm
author_sort Yasunori Fujimoto
collection DOAJ
description Objective The purpose of this study was to describe the endoscopic combined “transseptal/transnasal” approach with a pedicled nasoseptal flap for pituitary adenoma and skull base reconstruction, especially with respect to cerebrospinal fluid (CSF) fistula.Method Ninety-one consecutive patients with pituitary adenomas were retrospectively reviewed. All patients underwent the endoscopic combined “transseptal/transnasal” approach by the single team including the otorhinolaryngologists and neurosurgeons. Postoperative complications related to the flap were analyzed.Results Intra- and postoperative CSF fistulae were observed in 36 (40%) and 4 (4.4%) patients, respectively. Among the 4 patients, lumbar drainage and bed rest healed the CSF fistula in 3 patients and reoperation for revision was necessary in one patient. Other flap-related complications included nasal bleeding in 3 patients (3.3%).Conclusion The endoscopic combined “transseptal/transnasal” approach is most suitable for a two-surgeon technique and a pedicled nasoseptal flap is a reliable technique for preventing postoperative CSF fistula in pituitary surgery.
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spelling doaj-art-079361f175fa4c8ebe99b746f9c942cc2025-08-20T01:59:12ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272015-07-0173761161510.1590/0004-282X20150070S0004-282X2015000700611Endoscopic combined “transseptal/transnasal” approach for pituitary adenoma: reconstruction of skull base using pedicled nasoseptal flap in 91 consecutive casesYasunori FujimotoLeonardo BalsalobreFábio P. SantosEduardo VellutiniAldo C. StammObjective The purpose of this study was to describe the endoscopic combined “transseptal/transnasal” approach with a pedicled nasoseptal flap for pituitary adenoma and skull base reconstruction, especially with respect to cerebrospinal fluid (CSF) fistula.Method Ninety-one consecutive patients with pituitary adenomas were retrospectively reviewed. All patients underwent the endoscopic combined “transseptal/transnasal” approach by the single team including the otorhinolaryngologists and neurosurgeons. Postoperative complications related to the flap were analyzed.Results Intra- and postoperative CSF fistulae were observed in 36 (40%) and 4 (4.4%) patients, respectively. Among the 4 patients, lumbar drainage and bed rest healed the CSF fistula in 3 patients and reoperation for revision was necessary in one patient. Other flap-related complications included nasal bleeding in 3 patients (3.3%).Conclusion The endoscopic combined “transseptal/transnasal” approach is most suitable for a two-surgeon technique and a pedicled nasoseptal flap is a reliable technique for preventing postoperative CSF fistula in pituitary surgery.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000700611&lng=en&tlng=enfístulas líquido cefalorraquidianoacesso endoscópico endonasalflap naso-septal pediculadoadenoma de hipófise
spellingShingle Yasunori Fujimoto
Leonardo Balsalobre
Fábio P. Santos
Eduardo Vellutini
Aldo C. Stamm
Endoscopic combined “transseptal/transnasal” approach for pituitary adenoma: reconstruction of skull base using pedicled nasoseptal flap in 91 consecutive cases
Arquivos de Neuro-Psiquiatria
fístulas líquido cefalorraquidiano
acesso endoscópico endonasal
flap naso-septal pediculado
adenoma de hipófise
title Endoscopic combined “transseptal/transnasal” approach for pituitary adenoma: reconstruction of skull base using pedicled nasoseptal flap in 91 consecutive cases
title_full Endoscopic combined “transseptal/transnasal” approach for pituitary adenoma: reconstruction of skull base using pedicled nasoseptal flap in 91 consecutive cases
title_fullStr Endoscopic combined “transseptal/transnasal” approach for pituitary adenoma: reconstruction of skull base using pedicled nasoseptal flap in 91 consecutive cases
title_full_unstemmed Endoscopic combined “transseptal/transnasal” approach for pituitary adenoma: reconstruction of skull base using pedicled nasoseptal flap in 91 consecutive cases
title_short Endoscopic combined “transseptal/transnasal” approach for pituitary adenoma: reconstruction of skull base using pedicled nasoseptal flap in 91 consecutive cases
title_sort endoscopic combined transseptal transnasal approach for pituitary adenoma reconstruction of skull base using pedicled nasoseptal flap in 91 consecutive cases
topic fístulas líquido cefalorraquidiano
acesso endoscópico endonasal
flap naso-septal pediculado
adenoma de hipófise
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000700611&lng=en&tlng=en
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