Skin Microbiome Composition and Key Factors of its Barrier Function
The skin is the largest organ of the human body, it creates protective barrier between the internal and external environment. Skin barrier damage may result in homeostasis imbalance, inflammation, or bacterial infection. The microbiome plays a crucial role in maintaining normal skin functioning: con...
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| Format: | Article |
| Language: | English |
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"Paediatrician" Publishers LLC
2023-11-01
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| Series: | Вопросы современной педиатрии |
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| Online Access: | https://vsp.spr-journal.ru/jour/article/view/3299 |
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| author | Nikolay N. Murashkin Ekaterina S. Pavlova Roman V. Epishev Alexander I. Materikin Roman A. Ivanov Alena A. Savelova Dmitriy V. Fedorov Maria A. Leonova |
| author_facet | Nikolay N. Murashkin Ekaterina S. Pavlova Roman V. Epishev Alexander I. Materikin Roman A. Ivanov Alena A. Savelova Dmitriy V. Fedorov Maria A. Leonova |
| author_sort | Nikolay N. Murashkin |
| collection | DOAJ |
| description | The skin is the largest organ of the human body, it creates protective barrier between the internal and external environment. Skin barrier damage may result in homeostasis imbalance, inflammation, or bacterial infection. The microbiome plays a crucial role in maintaining normal skin functioning: control of pathogenic diversity of microorganisms, stimulate immune cells, and modulate chronic dermatoses development. There are various mechanisms for restoring skin barrier function. They are associated with the microorganisms’ activity. Thus, skin restoration is an important task included in the general concept of atopic dermatitis management. One of such methods is the skin surface colonization with commensals, so significant role is assigned to the new dermatological drugs. The normalization of the microbiome in affected skin areas with cosmetic care products can significantly affect the result of skin barrier restoration. |
| format | Article |
| id | doaj-art-078f418d786a4bc39dafbbc2773fcc2a |
| institution | DOAJ |
| issn | 1682-5527 1682-5535 |
| language | English |
| publishDate | 2023-11-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj-art-078f418d786a4bc39dafbbc2773fcc2a2025-08-20T03:21:55Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352023-11-0122538739210.15690/vsp.v22i5.26242122Skin Microbiome Composition and Key Factors of its Barrier FunctionNikolay N. Murashkin0Ekaterina S. Pavlova1Roman V. Epishev2Alexander I. Materikin3Roman A. Ivanov4Alena A. Savelova5Dmitriy V. Fedorov6Maria A. Leonova7National Medical Research Center of Children’s Health; Sechenov First Moscow State Medical University; Central State Medical Academy of Department of Presidential AffairsNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthThe skin is the largest organ of the human body, it creates protective barrier between the internal and external environment. Skin barrier damage may result in homeostasis imbalance, inflammation, or bacterial infection. The microbiome plays a crucial role in maintaining normal skin functioning: control of pathogenic diversity of microorganisms, stimulate immune cells, and modulate chronic dermatoses development. There are various mechanisms for restoring skin barrier function. They are associated with the microorganisms’ activity. Thus, skin restoration is an important task included in the general concept of atopic dermatitis management. One of such methods is the skin surface colonization with commensals, so significant role is assigned to the new dermatological drugs. The normalization of the microbiome in affected skin areas with cosmetic care products can significantly affect the result of skin barrier restoration.https://vsp.spr-journal.ru/jour/article/view/3299microbiomeskin barrieratopic dermatitisprebioticsprobiotics |
| spellingShingle | Nikolay N. Murashkin Ekaterina S. Pavlova Roman V. Epishev Alexander I. Materikin Roman A. Ivanov Alena A. Savelova Dmitriy V. Fedorov Maria A. Leonova Skin Microbiome Composition and Key Factors of its Barrier Function Вопросы современной педиатрии microbiome skin barrier atopic dermatitis prebiotics probiotics |
| title | Skin Microbiome Composition and Key Factors of its Barrier Function |
| title_full | Skin Microbiome Composition and Key Factors of its Barrier Function |
| title_fullStr | Skin Microbiome Composition and Key Factors of its Barrier Function |
| title_full_unstemmed | Skin Microbiome Composition and Key Factors of its Barrier Function |
| title_short | Skin Microbiome Composition and Key Factors of its Barrier Function |
| title_sort | skin microbiome composition and key factors of its barrier function |
| topic | microbiome skin barrier atopic dermatitis prebiotics probiotics |
| url | https://vsp.spr-journal.ru/jour/article/view/3299 |
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