Unmasking the Silent Danger: A Case Series of Wellens’ Syndrome and Its Implications for Early Intervention
Wellens’ syndrome represents a critical Electrocardiographic (ECG) pattern indicative of severe proximal Left Anterior Descending (LAD) coronary artery stenosis, demanding urgent diagnosis and treatment. This case series details four patients with diverse clinical presentations and risk factors, all...
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JCDR Research and Publications Private Limited
2025-05-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/20973/78572_CE[Ra1]_F(SHU)_QC_PF1(HJ_SS)_PFA_NC(IS)_PN(IS).pdf |
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| author | Hariharan Narasaiyan N Swaminathan |
| author_facet | Hariharan Narasaiyan N Swaminathan |
| author_sort | Hariharan Narasaiyan |
| collection | DOAJ |
| description | Wellens’ syndrome represents a critical Electrocardiographic (ECG) pattern indicative of severe proximal Left Anterior Descending (LAD) coronary artery stenosis, demanding urgent diagnosis and treatment. This case series details four patients with diverse clinical presentations and risk factors, all exhibiting Wellens’ syndrome. The cases illustrate both classic ECG features-biphasic or deeply inverted T waves in precordial leads-and atypical features, such as biphasic T-wave inversion extending to lateral leads and post-prandial chest pain in a patient with prior right coronary artery Percutaneous Coronary Intervention (PCI). This series underscores the need for clinicians to maintain a low threshold of suspicion for Wellens’ syndrome, even with atypical signs and low troponin levels. Each patient underwent coronary angiography revealing significant LAD stenosis, followed by successful PCI and secondary prevention strategies. These cases highlight the importance of recognising Wellens’ syndrome and the urgency of diagnosis and treatment to prevent major adverse cardiac events. |
| format | Article |
| id | doaj-art-078ccda6d8da4fbea31e4b8982115390 |
| institution | OA Journals |
| issn | 2249-782X 0973-709X |
| language | English |
| publishDate | 2025-05-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj-art-078ccda6d8da4fbea31e4b89821153902025-08-20T02:31:11ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2025-05-01195OR01OR0310.7860/JCDR/2025/78572.20973Unmasking the Silent Danger: A Case Series of Wellens’ Syndrome and Its Implications for Early InterventionHariharan Narasaiyan0N Swaminathan1Associate Professor, Department of Electrophysiology and Pacing, Christian Medical College, Vellore, Tamil Nadu, India.Professor (Rtd), Department of Cardiology, Madras Medical College, Chennai, Tamil Nadu, India.Wellens’ syndrome represents a critical Electrocardiographic (ECG) pattern indicative of severe proximal Left Anterior Descending (LAD) coronary artery stenosis, demanding urgent diagnosis and treatment. This case series details four patients with diverse clinical presentations and risk factors, all exhibiting Wellens’ syndrome. The cases illustrate both classic ECG features-biphasic or deeply inverted T waves in precordial leads-and atypical features, such as biphasic T-wave inversion extending to lateral leads and post-prandial chest pain in a patient with prior right coronary artery Percutaneous Coronary Intervention (PCI). This series underscores the need for clinicians to maintain a low threshold of suspicion for Wellens’ syndrome, even with atypical signs and low troponin levels. Each patient underwent coronary angiography revealing significant LAD stenosis, followed by successful PCI and secondary prevention strategies. These cases highlight the importance of recognising Wellens’ syndrome and the urgency of diagnosis and treatment to prevent major adverse cardiac events.https://jcdr.net/articles/PDF/20973/78572_CE[Ra1]_F(SHU)_QC_PF1(HJ_SS)_PFA_NC(IS)_PN(IS).pdfcardiac biomarkersleft anterior descending artery stenosismyocardial infarctiont wave inversion |
| spellingShingle | Hariharan Narasaiyan N Swaminathan Unmasking the Silent Danger: A Case Series of Wellens’ Syndrome and Its Implications for Early Intervention Journal of Clinical and Diagnostic Research cardiac biomarkers left anterior descending artery stenosis myocardial infarction t wave inversion |
| title | Unmasking the Silent Danger: A Case Series of Wellens’ Syndrome and Its Implications for Early Intervention |
| title_full | Unmasking the Silent Danger: A Case Series of Wellens’ Syndrome and Its Implications for Early Intervention |
| title_fullStr | Unmasking the Silent Danger: A Case Series of Wellens’ Syndrome and Its Implications for Early Intervention |
| title_full_unstemmed | Unmasking the Silent Danger: A Case Series of Wellens’ Syndrome and Its Implications for Early Intervention |
| title_short | Unmasking the Silent Danger: A Case Series of Wellens’ Syndrome and Its Implications for Early Intervention |
| title_sort | unmasking the silent danger a case series of wellens syndrome and its implications for early intervention |
| topic | cardiac biomarkers left anterior descending artery stenosis myocardial infarction t wave inversion |
| url | https://jcdr.net/articles/PDF/20973/78572_CE[Ra1]_F(SHU)_QC_PF1(HJ_SS)_PFA_NC(IS)_PN(IS).pdf |
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