SACU-Net: Shape-Aware U-Net for Biomedical Image Segmentation With Attention Mechanism and Context Extraction

With the rapid development of convolutional neural networks in image processing, deep learning has been widely applied to medical image segmentation tasks, including liver, retinal vessels, nuclei, and COVID-19 lesion segmentation. However, the accuracy and interpretability of these methods still ne...

Full description

Saved in:
Bibliographic Details
Main Authors: Yinuo Cao, Yong Cheng
Format: Article
Language:English
Published: IEEE 2025-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/10829919/
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1841542519185211392
author Yinuo Cao
Yong Cheng
author_facet Yinuo Cao
Yong Cheng
author_sort Yinuo Cao
collection DOAJ
description With the rapid development of convolutional neural networks in image processing, deep learning has been widely applied to medical image segmentation tasks, including liver, retinal vessels, nuclei, and COVID-19 lesion segmentation. However, the accuracy and interpretability of these methods still need further improvement. This paper proposes a novel Shape-aware U-Net architecture with Attention Mechanism and Context Extraction (SACU-Net) to address the aforementioned issues regarding segmentation performance and shape identification. Our model introduces three major modifications to the standard U-Net: 1) a new context extraction module block (MRC) to capture high-level context features, 2) redesigned skip pathways with spatial and channel attention mechanisms to reduce the semantic gap between the feature maps of encoder and decoder sub-networks, and 3) a novel loss function to enhance segmentation accuracy. We have evaluated SACU-Net against various U-Net variants on four different medical image segmentation tasks: liver segmentation in abdominal CT scans, retinal vessel segmentation, nuclei segmentation, and COVID-19 lesion segmentation. The results demonstrate relative improvements in performance of 7.30%, 5.5%, and 8.40% compared to state-of-the-art U-Net variants.
format Article
id doaj-art-0784adc8358b49caa48d4259425dfbdd
institution Kabale University
issn 2169-3536
language English
publishDate 2025-01-01
publisher IEEE
record_format Article
series IEEE Access
spelling doaj-art-0784adc8358b49caa48d4259425dfbdd2025-01-14T00:02:43ZengIEEEIEEE Access2169-35362025-01-01135719573010.1109/ACCESS.2025.352660210829919SACU-Net: Shape-Aware U-Net for Biomedical Image Segmentation With Attention Mechanism and Context ExtractionYinuo Cao0https://orcid.org/0009-0006-2415-4372Yong Cheng1https://orcid.org/0000-0002-9057-2007Department of Statistics, The Ohio State University, Columbus, OH, USASchool of Information Science and Technology, Beijing University of Chemical Technology, Beijing, ChinaWith the rapid development of convolutional neural networks in image processing, deep learning has been widely applied to medical image segmentation tasks, including liver, retinal vessels, nuclei, and COVID-19 lesion segmentation. However, the accuracy and interpretability of these methods still need further improvement. This paper proposes a novel Shape-aware U-Net architecture with Attention Mechanism and Context Extraction (SACU-Net) to address the aforementioned issues regarding segmentation performance and shape identification. Our model introduces three major modifications to the standard U-Net: 1) a new context extraction module block (MRC) to capture high-level context features, 2) redesigned skip pathways with spatial and channel attention mechanisms to reduce the semantic gap between the feature maps of encoder and decoder sub-networks, and 3) a novel loss function to enhance segmentation accuracy. We have evaluated SACU-Net against various U-Net variants on four different medical image segmentation tasks: liver segmentation in abdominal CT scans, retinal vessel segmentation, nuclei segmentation, and COVID-19 lesion segmentation. The results demonstrate relative improvements in performance of 7.30%, 5.5%, and 8.40% compared to state-of-the-art U-Net variants.https://ieeexplore.ieee.org/document/10829919/Medical image segmentationU-NetCNNdeep learningattention mechanism
spellingShingle Yinuo Cao
Yong Cheng
SACU-Net: Shape-Aware U-Net for Biomedical Image Segmentation With Attention Mechanism and Context Extraction
IEEE Access
Medical image segmentation
U-Net
CNN
deep learning
attention mechanism
title SACU-Net: Shape-Aware U-Net for Biomedical Image Segmentation With Attention Mechanism and Context Extraction
title_full SACU-Net: Shape-Aware U-Net for Biomedical Image Segmentation With Attention Mechanism and Context Extraction
title_fullStr SACU-Net: Shape-Aware U-Net for Biomedical Image Segmentation With Attention Mechanism and Context Extraction
title_full_unstemmed SACU-Net: Shape-Aware U-Net for Biomedical Image Segmentation With Attention Mechanism and Context Extraction
title_short SACU-Net: Shape-Aware U-Net for Biomedical Image Segmentation With Attention Mechanism and Context Extraction
title_sort sacu net shape aware u net for biomedical image segmentation with attention mechanism and context extraction
topic Medical image segmentation
U-Net
CNN
deep learning
attention mechanism
url https://ieeexplore.ieee.org/document/10829919/
work_keys_str_mv AT yinuocao sacunetshapeawareunetforbiomedicalimagesegmentationwithattentionmechanismandcontextextraction
AT yongcheng sacunetshapeawareunetforbiomedicalimagesegmentationwithattentionmechanismandcontextextraction