Compressible, anti-fatigue, extreme environment adaptable, and biocompatible supramolecular organohydrogel enabled by lignosulfonate triggered noncovalent network
Abstract Achieving a synergy of biocompatibility and extreme environmental adaptability with excellent mechanical property remains challenging in the development of synthetic materials. Herein, a “bottom-up” solution-interface-induced self-assembly strategy is adopted to develop a compressible, anti...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-024-55530-1 |
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| author | Yihui Gu Chao Xu Yilin Wang Jing Luo Dongsheng Shi Wenjuan Wu Lu Chen Yongcan Jin Bo Jiang Chaoji Chen |
| author_facet | Yihui Gu Chao Xu Yilin Wang Jing Luo Dongsheng Shi Wenjuan Wu Lu Chen Yongcan Jin Bo Jiang Chaoji Chen |
| author_sort | Yihui Gu |
| collection | DOAJ |
| description | Abstract Achieving a synergy of biocompatibility and extreme environmental adaptability with excellent mechanical property remains challenging in the development of synthetic materials. Herein, a “bottom-up” solution-interface-induced self-assembly strategy is adopted to develop a compressible, anti-fatigue, extreme environment adaptable, biocompatible, and recyclable organohydrogel composed of chitosan-lignosulfonate-gelatin by constructing noncovalent bonded conjoined network. The ethylene glycol/water solvent induced lignosulfonate nanoparticles function as bridge in chitosan/gelation network, forming multiple interfacial interactions that can effectively dissipate energy. The organohydrogel exhibits high compressive strength (54 MPa) and toughness (3.54 MJ/m3), 100 and 70 times higher than those of pure chitosan/gelatin hydrogel, meanwhile, excellent self-recovery and fatigue resistance properties. Even when subjected to severe compression up to a strain of 0.5 for 500,000 cycles, the organohydrogel still remains intact. This organohydrogel also demonstrates notable biocompatibility both in vivo and vitro, environment adaptability at low temperature, as well as recyclability. Such all natural organohydrogel provides a promising route towards the development of high-performance load-bearing materials. |
| format | Article |
| id | doaj-art-0777b60d49ac4203a462f0b1ba429c27 |
| institution | DOAJ |
| issn | 2041-1723 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj-art-0777b60d49ac4203a462f0b1ba429c272025-08-20T02:46:07ZengNature PortfolioNature Communications2041-17232025-01-0116111310.1038/s41467-024-55530-1Compressible, anti-fatigue, extreme environment adaptable, and biocompatible supramolecular organohydrogel enabled by lignosulfonate triggered noncovalent networkYihui Gu0Chao Xu1Yilin Wang2Jing Luo3Dongsheng Shi4Wenjuan Wu5Lu Chen6Yongcan Jin7Bo Jiang8Chaoji Chen9Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, College of Light Industry and Food Engineering, Nanjing Forestry UniversityHubei Biomass-Resource Chemistry and Environmental Biotechnology Key Laboratory, Hubei Provincial Engineering Research Center of Emerging Functional Coating Materials, School of Resource and Environmental Sciences, Wuhan UniversityJiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, College of Light Industry and Food Engineering, Nanjing Forestry UniversityJiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, College of Light Industry and Food Engineering, Nanjing Forestry UniversityJiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, College of Light Industry and Food Engineering, Nanjing Forestry UniversityJiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, College of Light Industry and Food Engineering, Nanjing Forestry UniversityHubei Biomass-Resource Chemistry and Environmental Biotechnology Key Laboratory, Hubei Provincial Engineering Research Center of Emerging Functional Coating Materials, School of Resource and Environmental Sciences, Wuhan UniversityJiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, College of Light Industry and Food Engineering, Nanjing Forestry UniversityJiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, College of Light Industry and Food Engineering, Nanjing Forestry UniversityHubei Biomass-Resource Chemistry and Environmental Biotechnology Key Laboratory, Hubei Provincial Engineering Research Center of Emerging Functional Coating Materials, School of Resource and Environmental Sciences, Wuhan UniversityAbstract Achieving a synergy of biocompatibility and extreme environmental adaptability with excellent mechanical property remains challenging in the development of synthetic materials. Herein, a “bottom-up” solution-interface-induced self-assembly strategy is adopted to develop a compressible, anti-fatigue, extreme environment adaptable, biocompatible, and recyclable organohydrogel composed of chitosan-lignosulfonate-gelatin by constructing noncovalent bonded conjoined network. The ethylene glycol/water solvent induced lignosulfonate nanoparticles function as bridge in chitosan/gelation network, forming multiple interfacial interactions that can effectively dissipate energy. The organohydrogel exhibits high compressive strength (54 MPa) and toughness (3.54 MJ/m3), 100 and 70 times higher than those of pure chitosan/gelatin hydrogel, meanwhile, excellent self-recovery and fatigue resistance properties. Even when subjected to severe compression up to a strain of 0.5 for 500,000 cycles, the organohydrogel still remains intact. This organohydrogel also demonstrates notable biocompatibility both in vivo and vitro, environment adaptability at low temperature, as well as recyclability. Such all natural organohydrogel provides a promising route towards the development of high-performance load-bearing materials.https://doi.org/10.1038/s41467-024-55530-1 |
| spellingShingle | Yihui Gu Chao Xu Yilin Wang Jing Luo Dongsheng Shi Wenjuan Wu Lu Chen Yongcan Jin Bo Jiang Chaoji Chen Compressible, anti-fatigue, extreme environment adaptable, and biocompatible supramolecular organohydrogel enabled by lignosulfonate triggered noncovalent network Nature Communications |
| title | Compressible, anti-fatigue, extreme environment adaptable, and biocompatible supramolecular organohydrogel enabled by lignosulfonate triggered noncovalent network |
| title_full | Compressible, anti-fatigue, extreme environment adaptable, and biocompatible supramolecular organohydrogel enabled by lignosulfonate triggered noncovalent network |
| title_fullStr | Compressible, anti-fatigue, extreme environment adaptable, and biocompatible supramolecular organohydrogel enabled by lignosulfonate triggered noncovalent network |
| title_full_unstemmed | Compressible, anti-fatigue, extreme environment adaptable, and biocompatible supramolecular organohydrogel enabled by lignosulfonate triggered noncovalent network |
| title_short | Compressible, anti-fatigue, extreme environment adaptable, and biocompatible supramolecular organohydrogel enabled by lignosulfonate triggered noncovalent network |
| title_sort | compressible anti fatigue extreme environment adaptable and biocompatible supramolecular organohydrogel enabled by lignosulfonate triggered noncovalent network |
| url | https://doi.org/10.1038/s41467-024-55530-1 |
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