Association between age at menarche and the risk of myopia at the age of 15 in Chongqing, China: a cross-sectional study
IntroductionMenarche is one of the important indicators of girls’ physical, nutritional, and reproductive health. This study aims to identify the relationship between the age at menarche and the risk of myopia at the age of 15.MethodsGirls aged 15 were recruited when they visited the hospital for ph...
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Frontiers Media S.A.
2025-07-01
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2025.1590463/full |
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| author | Jing Zhang Ruili Li Yong Zhang Tian OuYang Dan Ao LiYan Gong Li He Xiaoya Qi Xiyuan Zhou |
| author_facet | Jing Zhang Ruili Li Yong Zhang Tian OuYang Dan Ao LiYan Gong Li He Xiaoya Qi Xiyuan Zhou |
| author_sort | Jing Zhang |
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| description | IntroductionMenarche is one of the important indicators of girls’ physical, nutritional, and reproductive health. This study aims to identify the relationship between the age at menarche and the risk of myopia at the age of 15.MethodsGirls aged 15 were recruited when they visited the hospital for physical examination required for enrollment in the high school. Eligible participants underwent anthropometric measurements and an ocular examination, and they completed a questionnaire to gather personal information, including age at menarche. Ocular indexes were compared across early, normal, and late menarche groups, and multivariate regression was performed to analyze the relationships between age at menarche and myopia.ResultsAmong the 376 participants around the age of 15, 115 girls were classified into the early menarche group, 185 into the normal menarche group, and 76 into the late menarche group. The prevalence of myopia was 95.7, 87.6, and 86.6% for the right eye (p = 0.048) and 89.6, 77.8, and 68.4% (p = 0.001) for the left eye in the early, middle, and late menarche groups, respectively. Age at menarche was negatively and significantly associated with myopia, particularly with moderate to severe myopia in 15-year-old girls (p = 0.039 for the right eye, p = 0.001 for the left eye).DiscussionAge at menarche, as a marker of the onset of puberty, was identified as an independent risk factor of myopia in teenage girls, particularly for moderate to severe myopia. This implies that accelerated physical development during puberty may contribute to the onset and progression of myopia in the context of modern lifestyles in urban China. Additional interventions should be considered for this subgroup of children. |
| format | Article |
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| institution | Kabale University |
| issn | 2296-858X |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj-art-076fa479ce884cea9b62e7f692fe28fd2025-08-20T03:50:40ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-07-011210.3389/fmed.2025.15904631590463Association between age at menarche and the risk of myopia at the age of 15 in Chongqing, China: a cross-sectional studyJing Zhang0Ruili Li1Yong Zhang2Tian OuYang3Dan Ao4LiYan Gong5Li He6Xiaoya Qi7Xiyuan Zhou8Department of Health Management Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, ChinaDepartment of Special Medical Service Centre, The First Affiliated Hospital of Chongqing Medical University, Chongqing, ChinaSchool of Public Health, Chongqing Medical University, Chongqing, ChinaSchool of Public Health, Chongqing Medical University, Chongqing, ChinaHealth Medicine Center, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, ChinaHealth Medicine Center, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, ChinaHealth Medicine Center, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, ChinaHealth Medicine Center, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, ChinaDepartment of Ophthalmology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, ChinaIntroductionMenarche is one of the important indicators of girls’ physical, nutritional, and reproductive health. This study aims to identify the relationship between the age at menarche and the risk of myopia at the age of 15.MethodsGirls aged 15 were recruited when they visited the hospital for physical examination required for enrollment in the high school. Eligible participants underwent anthropometric measurements and an ocular examination, and they completed a questionnaire to gather personal information, including age at menarche. Ocular indexes were compared across early, normal, and late menarche groups, and multivariate regression was performed to analyze the relationships between age at menarche and myopia.ResultsAmong the 376 participants around the age of 15, 115 girls were classified into the early menarche group, 185 into the normal menarche group, and 76 into the late menarche group. The prevalence of myopia was 95.7, 87.6, and 86.6% for the right eye (p = 0.048) and 89.6, 77.8, and 68.4% (p = 0.001) for the left eye in the early, middle, and late menarche groups, respectively. Age at menarche was negatively and significantly associated with myopia, particularly with moderate to severe myopia in 15-year-old girls (p = 0.039 for the right eye, p = 0.001 for the left eye).DiscussionAge at menarche, as a marker of the onset of puberty, was identified as an independent risk factor of myopia in teenage girls, particularly for moderate to severe myopia. This implies that accelerated physical development during puberty may contribute to the onset and progression of myopia in the context of modern lifestyles in urban China. Additional interventions should be considered for this subgroup of children.https://www.frontiersin.org/articles/10.3389/fmed.2025.1590463/fullmyopiamenarche ageadolescentChinese girlspuberty |
| spellingShingle | Jing Zhang Ruili Li Yong Zhang Tian OuYang Dan Ao LiYan Gong Li He Xiaoya Qi Xiyuan Zhou Association between age at menarche and the risk of myopia at the age of 15 in Chongqing, China: a cross-sectional study Frontiers in Medicine myopia menarche age adolescent Chinese girls puberty |
| title | Association between age at menarche and the risk of myopia at the age of 15 in Chongqing, China: a cross-sectional study |
| title_full | Association between age at menarche and the risk of myopia at the age of 15 in Chongqing, China: a cross-sectional study |
| title_fullStr | Association between age at menarche and the risk of myopia at the age of 15 in Chongqing, China: a cross-sectional study |
| title_full_unstemmed | Association between age at menarche and the risk of myopia at the age of 15 in Chongqing, China: a cross-sectional study |
| title_short | Association between age at menarche and the risk of myopia at the age of 15 in Chongqing, China: a cross-sectional study |
| title_sort | association between age at menarche and the risk of myopia at the age of 15 in chongqing china a cross sectional study |
| topic | myopia menarche age adolescent Chinese girls puberty |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2025.1590463/full |
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