Optimized Enoxolone-Loaded Microsponges for Drug Delivery: A Design of Experiments Approach

Optimized Enoxolone-Loaded Microsponges for Drug Delivery: A Design of Experiments Approach

Enoxolon is widely recognized for its pharmacological potential, exhibiting antioxidant, anti-inflammatory, anticancer, and antiviral properties. <b>Objectives</b>: This study aimed to develop an enhanced formulation of enoxolone-loaded microsponges as a novel drug delivery system. A des...

Full description

Saved in:

Bibliographic Details
Main Authors:	Juste Baranauskaite, Sedef Sefer, Augusta Zevzikoviene, Andrejus Zevzikovas, Liudas Ivanauskas
Format:	Article
Language:	English
Published:	MDPI AG 2025-06-01
Series:	Pharmaceuticals
Subjects:	microsponges enoxolone chronic periodontitis
Online Access:	https://www.mdpi.com/1424-8247/18/7/938
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Application of Microsponge Drug Platform to Enhance Methotrexate Administration in Rheumatoid Arthritis Therapy
by: Noemi Fiaschini, et al.
Published: (2024-12-01)

Herbal microsponge gel for the treatment of cutaneous lupus erythematosus
by: Sweety Chheda, et al.
Published: (2025-06-01)

The comparative evaluation of 1% alendronate gel as local drug delivery system in chronic periodontitis in smokers and non smokers: Randomized clinical trial
by: Vidushi Sheokand, et al.
Published: (2019-04-01)

Ocular administration of acetazolamide microsponges in situ gel formulations
by: Manar M. Obiedallah, et al.
Published: (2018-11-01)

Clinical and Immunological Efficacy of an Eucalyptus Leaf Preparation in Chronic Periodontitis Treatment: A Randomized Interventional Longitudinal Clinical Study
by: A. A. Zub, et al.
Published: (2022-12-01)

Therapeutic Efficacy of Subgingivally Delivered Doxycycline Hyclate as an Adjunct to Non-surgical Treatment of Chronic Periodontitis
by: Vikas Deo, et al.
Published: (2011-01-01)

Combined lesion of endodont and periodontal in adults and its causes
by: P. V. Moroz, et al.
Published: (2020-03-01)

Plasma levels of immune system activation markers Neopterin and Kynurenine-to-Tryptophan Ratio, and oral health among community-dwelling adults in Norway: a population-based, cohort study
by: Sarala Banjara, et al.
Published: (2025-05-01)

Redondovirius-associated periodontitis in people with poor oral hygiene: a cross-sectional study
by: Alireza Mohebbi, et al.
Published: (2025-05-01)

Occupational conditionality of diseases of chronic generalized periodontitis and bruxism in limestone quarry workers
by: R. R. Khaibullina, et al.
Published: (2021-07-01)

Nanoparticle based periodontal drug delivery – A review on current trends and future perspectives
by: Amani Mohammed Basudan
Published: (2022-12-01)

Response to adjunctive antibiotic therapy along with nonsurgical periodontal therapy in the treatment of peri-implantitis and chronic periodontitis patients: An exploratory review
by: Geetanshu Sethi, et al.
Published: (2024-07-01)

Evaluating the effect of virgin coconut oil pulling on viral load, bacterial load and inflammatory mediator levels in chronic periodontitis – A clinical study
by: Monika M, et al.
Published: (2025-01-01)

Susceptibility of periodontal pathogens to a novel target-specific drug delivery system containing self-nanoemulsifying curcumin: An in vitro study
by: Veena HR, et al.
Published: (2023-12-01)

The influence of smoking on the levels of matrix metalloproteinase-8 and periodontal parameters in smoker and nonsmoker patients with chronic periodontitis: A clinicobiochemical study
by: Namita Gupta, et al.
Published: (2016-11-01)

Shotgun metagenomic analysis of the oral microbiome in gingivitis: a nested case-control study
by: Muhammed Manzoor, et al.
Published: (2024-12-01)

Neutrophil extracellular traps in the cross-talk between periodontitis and chronic kidney disease
by: Shucheng Hu, et al.
Published: (2024-11-01)

Clinical Study Comparing Herbal Plant Extract as a Supportive Treatment for Chronic Periodontitis
by: Lagdive Sushma Sanjay, et al.
Published: (2025-05-01)

An evaluation of generalized periodontitis treatment, based on diagnostics of pathological teeth mobility, using periotestometry. Clinical review
by: Т. І. Matviykiv
Published: (2017-10-01)

THE RESULTS OF THE USE OF SELENIUM IN THE COMPLEX TREATMENT OF PATIENTS WITH CHRONIC GENERALIZED PERIODONTITIS
by: A.E. Gorshkova
Published: (2019-12-01)

Histological characteristics of dental pulp in teeth with periodontal problems and healthy teeth
by: Farzane Vaziri, et al.
Published: (2023-06-01)

Microenvironment-sensitive hydrogels as promising drug delivery systems for co-encapsulating microbial homeostasis probiotics and anti-inflammatory drugs to treat periodontitis
by: Yi Quan, et al.
Published: (2025-06-01)

Advances in pH-responsive drug delivery systems for periodontitis treatment
by: Zhuomin Sha, et al.
Published: (2025-12-01)

Periodontal tray application of chlorine dioxide gel as an adjunct to scaling and root planing in the treatment of chronic periodontitis
by: Ira Komara, et al.
Published: (2020-05-01)

Anticancer properties of Cirsium vulgare (Savi) ten. Dry extracts from different plant parts and phenological stages of Raw material collection
by: Urtė Griškevičienė, et al.
Published: (2025-04-01)

Advances in Local Drug Delivery for Periodontal Treatment: Present Strategies and Future Directions
by: Mayuka Nakajima, et al.
Published: (2025-06-01)

Evaluation of the Effect of Phase 1 Periodontal Therapy on Serum Procoagulant State of Systemically Healthy Chronic Periodontitis Subjects: A Clinico-Biochemical Study
by: Sapna Raje, et al.
Published: (2025-06-01)

Role of CD117 and mast cells in periodontal diseases: Histological and immunohistochemical study
by: Fatin L. Khaphi, et al.
Published: (2025-03-01)

Study on the Clinical Efficacy of Combined Therapy with Minocycline Hydrochloride Ointment and Tinidazole for Chronic Periodontitis: Retrospective Study
by: Wu Q, et al.
Published: (2025-04-01)

Periodontal Disease and Obstructive Sleep Apnea: Shared Mechanisms, Clinical Implications, and Future Research Directions
by: Serena Incerti Parenti, et al.
Published: (2025-01-01)

The influence of chronic periodontitis and type 2 diabetes mellitus on resistin levels of gingival crevicular fluid- a systematic review and meta-analysis
by: Dax Abraham, et al.
Published: (2025-05-01)

Оптимизация лечения деструктивных форм хронического периодонтита с применением препаратов гидроокиси кальция
Published: (2020-04-01)

RESEARCH OF THERMOMETRIC INDICATORS OF THE GUM IN THE TREATMENT OF HARD TISSUES FURCATION PERFORATION
by: E. Ryabokon, et al.
Published: (2018-03-01)

Peculiarities of diagnostics and treatment of chronic generalized periodontitis in patients with heart rhythm disorders taking anticoagulants
by: M. V. Lomakina, et al.
Published: (2025-06-01)

Comparative evaluation of ozonized water versus normal saline irrigation with mechanical debridement in chronic periodontitis patients – A clinical study
by: G.N. Rohith, et al.
Published: (2025-05-01)

Effect of Systemic Doxycycline on Scaling and Root Planing in Chronic Periodontitis
by: Dhwani Vyas, et al.
Published: (2019-01-01)

Correlation between chronic periodontal disease and malnutrition-inflammation atherosclerosis (MIA) syndrome in maintenance hemodialysis patients
by: JIA Lin, et al.
Published: (2019-01-01)

Enhancing Periodontal Ligament Regeneration via PDLSC Delivery Using Electrospun PCL/Collagen/Cellulose Acetate Scaffolds and Collagen Hydrogel Incorporated with Curcumin-Loaded ZIF-8 Nanoparticles
by: Lan X, et al.
Published: (2025-01-01)

Features of the microbiota in chronic apical periodontitis. A systematic review
by: Z. S. Khabadze, et al.
Published: (2022-07-01)

Chlorhexidine–thymol varnish as an adjunct to scaling and root planing: A clinical observation
by: Vishal Anand, et al.
Published: (2012-05-01)