Transcriptional profile of the rat cardiovascular system at single-cell resolution

Transcriptional profile of the rat cardiovascular system at single-cell resolution

Summary: We sought to characterize cellular composition across the cardiovascular system of the healthy Wistar rat, an important model in preclinical cardiovascular research. We performed single-nucleus RNA sequencing (snRNA-seq) in 78 samples in 10 distinct regions, including the four chambers of t...

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Bibliographic Details
Main Authors: Alessandro Arduini, Stephen J. Fleming, Ling Xiao, Amelia W. Hall, Amer-Denis Akkad, Mark D. Chaffin, Kayla J. Bendinelli, Nathan R. Tucker, Irinna Papangeli, Helene Mantineo, Patricio Flores-Bringas, Mehrtash Babadi, Christian M. Stegmann, Guillermo García-Cardeña, Mark E. Lindsay, Carla Klattenhoff, Patrick T. Ellinor
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Cell Reports
Subjects:
CP: Developmental biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724014426
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