Ganoderma lucidum spore powder alleviates rheumatoid arthritis-associated pain hypersensitivity through inhibiting accumulation, N1 polarization, and ROS production of neutrophils in mice

Ganoderma lucidum spore powder alleviates rheumatoid arthritis-associated pain hypersensitivity through inhibiting accumulation, N1 polarization, and ROS production of neutrophils in mice

IntroductionRheumatoid arthritis (RA) is a chronic condition characterized by joint pain that significantly impairs patients’ work and daily lives. The limited understanding of the pathological mechanisms underlying RA-related pain poses challenges for effective clinical pain management. Ganoderma l...

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Bibliographic Details
Main Authors: Sen Huang, Zhaochun Zhan, Fei Xu, Xiaolin Liu, Zhenning Fang, Wenbo Wu, Zhile Liang, Guoguo Liu, Mengyuan Wang, Helena Soares da Silva, Xin Luo, Kai Mo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
Subjects:
rheumatoid arthritis
pain
neutrophils
Ganoderma lucidum spore powder
reactive oxygen species
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1569295/full
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