Clinical and Epidemiological Aspects of Ankylosing Spondylitis Patients in a Single Center in Baghdad
Ankylosing spondylitis is a chronic inflammatory disease with axial involvement but also may present as a peripheral arthritis and extraarticular manifestations. Objective: To assess clinical aspects of ankylosing spondylitis patients and different associated demographic variables in Baghdad teac...
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middle technical university
2022-03-01
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| Series: | Journal of Techniques |
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| Online Access: | https://journal.mtu.edu.iq/index.php/MTU/article/view/439 |
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| author | Ali Hussein Al Hafidh |
| author_facet | Ali Hussein Al Hafidh |
| author_sort | Ali Hussein Al Hafidh |
| collection | DOAJ |
| description |
Ankylosing spondylitis is a chronic inflammatory disease with axial involvement but also may present as a peripheral arthritis and extraarticular manifestations.
Objective: To assess clinical aspects of ankylosing spondylitis patients and different associated demographic variables in Baghdad teaching hospital.
Patients and methods: A cross-sectional study was carried out in Baghdad teaching hospital which includes 402 patients (≥ 18 years old) with a clinical diagnosis of AS according to Assessment of Spondylo Arthritis International Society for AS were involved in this study from June/2019 to June/2021. Demographic data and disease characteristics, presence of extra-articular manifestations (past and present) and measurement of disease activity was done by BASDAI, erythrocyte sedimentation rate (mm/h) and C-reactive protein (mg/L). In addition, HLAB27 typing was reported. Results: The age of onset for males was 24.87±8.8 and for females25.97±8.6 years, HLA typing HLA-B27 were 49.55% and 35.38% in males and females respectively and the association was found to be statistically significant (P. value =0.031). While family history was reported at 25.82% and 34.33% in males and females correspondingly. 75.07% of males compared to 71.38% of females were treated with Anti TNF therapy. Females had later onset of disease than males with lower percentage of HLA B27 positivity. Recommendation: more comprehensive assessment with advanced diagnostic and treatment standards.
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| format | Article |
| id | doaj-art-07642d64ebbd44aab715390b3b284d49 |
| institution | Kabale University |
| issn | 1818-653X 2708-8383 |
| language | English |
| publishDate | 2022-03-01 |
| publisher | middle technical university |
| record_format | Article |
| series | Journal of Techniques |
| spelling | doaj-art-07642d64ebbd44aab715390b3b284d492025-01-19T11:07:18Zengmiddle technical universityJournal of Techniques1818-653X2708-83832022-03-014110.51173/jt.v4i1.439Clinical and Epidemiological Aspects of Ankylosing Spondylitis Patients in a Single Center in BaghdadAli Hussein Al Hafidh0College of health and Medical Technology, Middle Technical University, Baghdad, Iraq Ankylosing spondylitis is a chronic inflammatory disease with axial involvement but also may present as a peripheral arthritis and extraarticular manifestations. Objective: To assess clinical aspects of ankylosing spondylitis patients and different associated demographic variables in Baghdad teaching hospital. Patients and methods: A cross-sectional study was carried out in Baghdad teaching hospital which includes 402 patients (≥ 18 years old) with a clinical diagnosis of AS according to Assessment of Spondylo Arthritis International Society for AS were involved in this study from June/2019 to June/2021. Demographic data and disease characteristics, presence of extra-articular manifestations (past and present) and measurement of disease activity was done by BASDAI, erythrocyte sedimentation rate (mm/h) and C-reactive protein (mg/L). In addition, HLAB27 typing was reported. Results: The age of onset for males was 24.87±8.8 and for females25.97±8.6 years, HLA typing HLA-B27 were 49.55% and 35.38% in males and females respectively and the association was found to be statistically significant (P. value =0.031). While family history was reported at 25.82% and 34.33% in males and females correspondingly. 75.07% of males compared to 71.38% of females were treated with Anti TNF therapy. Females had later onset of disease than males with lower percentage of HLA B27 positivity. Recommendation: more comprehensive assessment with advanced diagnostic and treatment standards. https://journal.mtu.edu.iq/index.php/MTU/article/view/439Ankylosing SpondylitisGenderHLA B27 PositivityUveitisDisease Activity |
| spellingShingle | Ali Hussein Al Hafidh Clinical and Epidemiological Aspects of Ankylosing Spondylitis Patients in a Single Center in Baghdad Journal of Techniques Ankylosing Spondylitis Gender HLA B27 Positivity Uveitis Disease Activity |
| title | Clinical and Epidemiological Aspects of Ankylosing Spondylitis Patients in a Single Center in Baghdad |
| title_full | Clinical and Epidemiological Aspects of Ankylosing Spondylitis Patients in a Single Center in Baghdad |
| title_fullStr | Clinical and Epidemiological Aspects of Ankylosing Spondylitis Patients in a Single Center in Baghdad |
| title_full_unstemmed | Clinical and Epidemiological Aspects of Ankylosing Spondylitis Patients in a Single Center in Baghdad |
| title_short | Clinical and Epidemiological Aspects of Ankylosing Spondylitis Patients in a Single Center in Baghdad |
| title_sort | clinical and epidemiological aspects of ankylosing spondylitis patients in a single center in baghdad |
| topic | Ankylosing Spondylitis Gender HLA B27 Positivity Uveitis Disease Activity |
| url | https://journal.mtu.edu.iq/index.php/MTU/article/view/439 |
| work_keys_str_mv | AT alihusseinalhafidh clinicalandepidemiologicalaspectsofankylosingspondylitispatientsinasinglecenterinbaghdad |