Integrating network pharmacology, in silico molecular docking and experimental validation to explain the anticancer, apoptotic, and anti-metastatic effects of cosmosiin natural product against human lung carcinoma
This research aimed to examine the anticancer properties of cosmosiin, a natural flavonoid, on human lung carcinoma cells by in silico molecular docking, network pharmacology, and in vitro experiments.
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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De Gruyter
2025-03-01
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| Series: | Türk Biyokimya Dergisi |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/tjb-2024-0225 |
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| _version_ | 1849731358112350208 |
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| author | Gu Qin Pan Xiaofei Ding Hui He Yuan Liu Kan |
| author_facet | Gu Qin Pan Xiaofei Ding Hui He Yuan Liu Kan |
| author_sort | Gu Qin |
| collection | DOAJ |
| description | This research aimed to examine the anticancer properties of cosmosiin, a natural flavonoid, on human lung carcinoma cells by in silico molecular docking, network pharmacology, and in vitro experiments. |
| format | Article |
| id | doaj-art-07582e4522dc46e9afc8ea7079c34b08 |
| institution | DOAJ |
| issn | 1303-829X |
| language | English |
| publishDate | 2025-03-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Türk Biyokimya Dergisi |
| spelling | doaj-art-07582e4522dc46e9afc8ea7079c34b082025-08-20T03:08:35ZengDe GruyterTürk Biyokimya Dergisi1303-829X2025-03-0150342943910.1515/tjb-2024-0225Integrating network pharmacology, in silico molecular docking and experimental validation to explain the anticancer, apoptotic, and anti-metastatic effects of cosmosiin natural product against human lung carcinomaGu Qin0Pan Xiaofei1Ding Hui2He Yuan3Liu Kan4Department of Comprehensive Internal Medicine, Chengdu Chenghua Sansong Kidney Disease Hospital, Chengdu Si Chuan, ChinaHealth Management Center, Yantai Qishan Hospital, Yantai Shandong, ChinaDepartment of Respiratory and Critical Care Medicine, Yixing People’s Hospital, Wuxi Jiangsu, ChinaDepartment of Respiratory and Critical Care Medicine, Yixing People’s Hospital, Wuxi Jiangsu, ChinaDepartment of Respiratory and Critical Care Medicine, Yixing People’s Hospital, Wuxi Jiangsu, ChinaThis research aimed to examine the anticancer properties of cosmosiin, a natural flavonoid, on human lung carcinoma cells by in silico molecular docking, network pharmacology, and in vitro experiments.https://doi.org/10.1515/tjb-2024-0225cosmosiinlung cancerin silico molecular dockingnetwork pharmacologyapoptosis |
| spellingShingle | Gu Qin Pan Xiaofei Ding Hui He Yuan Liu Kan Integrating network pharmacology, in silico molecular docking and experimental validation to explain the anticancer, apoptotic, and anti-metastatic effects of cosmosiin natural product against human lung carcinoma Türk Biyokimya Dergisi cosmosiin lung cancer in silico molecular docking network pharmacology apoptosis |
| title | Integrating network pharmacology, in silico molecular docking and experimental validation to explain the anticancer, apoptotic, and anti-metastatic effects of cosmosiin natural product against human lung carcinoma |
| title_full | Integrating network pharmacology, in silico molecular docking and experimental validation to explain the anticancer, apoptotic, and anti-metastatic effects of cosmosiin natural product against human lung carcinoma |
| title_fullStr | Integrating network pharmacology, in silico molecular docking and experimental validation to explain the anticancer, apoptotic, and anti-metastatic effects of cosmosiin natural product against human lung carcinoma |
| title_full_unstemmed | Integrating network pharmacology, in silico molecular docking and experimental validation to explain the anticancer, apoptotic, and anti-metastatic effects of cosmosiin natural product against human lung carcinoma |
| title_short | Integrating network pharmacology, in silico molecular docking and experimental validation to explain the anticancer, apoptotic, and anti-metastatic effects of cosmosiin natural product against human lung carcinoma |
| title_sort | integrating network pharmacology in silico molecular docking and experimental validation to explain the anticancer apoptotic and anti metastatic effects of cosmosiin natural product against human lung carcinoma |
| topic | cosmosiin lung cancer in silico molecular docking network pharmacology apoptosis |
| url | https://doi.org/10.1515/tjb-2024-0225 |
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