Inactivated Mycobacterial Vaccine Nebulized Inhalation: A Effective Therapy for the Prevention and Treatment of Respiratory Diseases?
ABSTRACT Nebulized inhalation therapy is an important method in the prevention and treatment of respiratory diseases, and inactivated mycobacterial vaccine nebulized inhalation has received a wide attention recently, but the roles and mechanisms are still not fully understood. A literature search sh...
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | The Clinical Respiratory Journal |
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| Online Access: | https://doi.org/10.1111/crj.70101 |
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| author | Xiaohong Jiang Qixiang Sun Yujia Huang Yuetian Deng Chaoqian Li |
| author_facet | Xiaohong Jiang Qixiang Sun Yujia Huang Yuetian Deng Chaoqian Li |
| author_sort | Xiaohong Jiang |
| collection | DOAJ |
| description | ABSTRACT Nebulized inhalation therapy is an important method in the prevention and treatment of respiratory diseases, and inactivated mycobacterial vaccine nebulized inhalation has received a wide attention recently, but the roles and mechanisms are still not fully understood. A literature search showed there is a strong scientific rationale and evidence that nebulized inhalation of inactivated mycobacterial vaccine is effective in the prevention and treatment of respiratory diseases. Clinically available mycobacterial vaccines include Mycobacterium phlei (M. phlei), BCG, and Mycobacterium vaccae (M. vaccae). Nebulized inhalation of inactivated mycobacterial vaccine, especially M. vaccae, has been used in the prevention and treatment of respiratory diseases, such as asthma, respiratory syncytial virus (RSV), coronavirus disease 2019 (COVID‐19), and sepsis. It acts on the respiratory tract directly, thus stimulating the body to produce an immune response, enhance respiratory immunity, and achieve prevention and treatment effects. Nebulized inhalation of inactivated mycobacterial vaccine will be an effective therapy in the prevention and treatment of respiratory diseases. |
| format | Article |
| id | doaj-art-0752d45eb2d84742a790f485fd281ae5 |
| institution | DOAJ |
| issn | 1752-6981 1752-699X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Clinical Respiratory Journal |
| spelling | doaj-art-0752d45eb2d84742a790f485fd281ae52025-08-20T02:48:42ZengWileyThe Clinical Respiratory Journal1752-69811752-699X2025-01-01197n/an/a10.1111/crj.70101Inactivated Mycobacterial Vaccine Nebulized Inhalation: A Effective Therapy for the Prevention and Treatment of Respiratory Diseases?Xiaohong Jiang0Qixiang Sun1Yujia Huang2Yuetian Deng3Chaoqian Li4Department of Geriatric Respiratory Medicine The First Affiliated Hospital of Guangxi Medical University Nanning Guangxi ChinaDepartment of Geriatric Respiratory Medicine The First Affiliated Hospital of Guangxi Medical University Nanning Guangxi ChinaDepartment of Respiratory and Critical Care Medicine Affiliated Hospital of Youjiang Medical University for Nationalities Baise Guangxi ChinaDepartment of Endocrinology Medicine, Cadre Ward Guangxi Medical University Kaiyuan Langdong Hospital Nanning Guangxi ChinaDepartment of Emergency The First Affiliated Hospital of Guangxi Medical University Nanning Guangxi ChinaABSTRACT Nebulized inhalation therapy is an important method in the prevention and treatment of respiratory diseases, and inactivated mycobacterial vaccine nebulized inhalation has received a wide attention recently, but the roles and mechanisms are still not fully understood. A literature search showed there is a strong scientific rationale and evidence that nebulized inhalation of inactivated mycobacterial vaccine is effective in the prevention and treatment of respiratory diseases. Clinically available mycobacterial vaccines include Mycobacterium phlei (M. phlei), BCG, and Mycobacterium vaccae (M. vaccae). Nebulized inhalation of inactivated mycobacterial vaccine, especially M. vaccae, has been used in the prevention and treatment of respiratory diseases, such as asthma, respiratory syncytial virus (RSV), coronavirus disease 2019 (COVID‐19), and sepsis. It acts on the respiratory tract directly, thus stimulating the body to produce an immune response, enhance respiratory immunity, and achieve prevention and treatment effects. Nebulized inhalation of inactivated mycobacterial vaccine will be an effective therapy in the prevention and treatment of respiratory diseases.https://doi.org/10.1111/crj.70101BCGinactivatedmycobacterial vaccineMycobacterium phleiMycobacterium vaccaenebulized inhalation |
| spellingShingle | Xiaohong Jiang Qixiang Sun Yujia Huang Yuetian Deng Chaoqian Li Inactivated Mycobacterial Vaccine Nebulized Inhalation: A Effective Therapy for the Prevention and Treatment of Respiratory Diseases? The Clinical Respiratory Journal BCG inactivated mycobacterial vaccine Mycobacterium phlei Mycobacterium vaccae nebulized inhalation |
| title | Inactivated Mycobacterial Vaccine Nebulized Inhalation: A Effective Therapy for the Prevention and Treatment of Respiratory Diseases? |
| title_full | Inactivated Mycobacterial Vaccine Nebulized Inhalation: A Effective Therapy for the Prevention and Treatment of Respiratory Diseases? |
| title_fullStr | Inactivated Mycobacterial Vaccine Nebulized Inhalation: A Effective Therapy for the Prevention and Treatment of Respiratory Diseases? |
| title_full_unstemmed | Inactivated Mycobacterial Vaccine Nebulized Inhalation: A Effective Therapy for the Prevention and Treatment of Respiratory Diseases? |
| title_short | Inactivated Mycobacterial Vaccine Nebulized Inhalation: A Effective Therapy for the Prevention and Treatment of Respiratory Diseases? |
| title_sort | inactivated mycobacterial vaccine nebulized inhalation a effective therapy for the prevention and treatment of respiratory diseases |
| topic | BCG inactivated mycobacterial vaccine Mycobacterium phlei Mycobacterium vaccae nebulized inhalation |
| url | https://doi.org/10.1111/crj.70101 |
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