BEHAVIORAL AND BIO-PSYCHO-SOCIAL FACTORS IN CANCER SURVIVORSHIP

The incidence of cancer continues to rise, with over 26 million cancer survivors projected by 2040. As survival rates improve, attention must shift toward comprehensively addressing the needs of cancer survivors, not only including prevention of cancer recurrence, but also extending to surveillan...

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Main Author: Antonino Di Meglio
Format: Article
Language:English
Published: Edisciences 2024-12-01
Series:Journal of Cancer Rehabilitation
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Online Access:https://www.edisciences.org/vol-7-issue-4-special-issue-jcr-ottobre-24-behavioral-and-bio-psycho-social-factors
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author Antonino Di Meglio
author_facet Antonino Di Meglio
author_sort Antonino Di Meglio
collection DOAJ
description The incidence of cancer continues to rise, with over 26 million cancer survivors projected by 2040. As survival rates improve, attention must shift toward comprehensively addressing the needs of cancer survivors, not only including prevention of cancer recurrence, but also extending to surveillance and management of physical and psychosocial effects. However, current practices reveal suboptimal engagement in key survivorship services such as health promotion as well as in management of long-term treatment-related symptoms, which can signifcantly impact survivors' quality of life, and also affect medication adherence and, ultimately, clinical outcomes. Predisposition to clinically meaningful symptom burden after cancer and cancer-related frailty represents signifcant risks for a substantial portion of cancer survivors and such risks seem to be driven by multiple individual factors such as age, comorbidities, lifestyle, psycho-social traits, baseline symptom burden pre-treatment, and type of treatment received. An additional important role seem to be played by susceptibility to cancer- induced infammation and accelerated aging. Emerging bio-behavioral models can now help identify patients at higher risk of long-term effects. Interventions targeting modifable factors, like excess weight, poor diet, inactivity, and stress, can address risk factors, and some of them act through mitigation of systemic infammation. Many of these behavioral interventions are multi-target and can also be delivered digitally and/or self-administered. Moving forward, by leveraging knowledge of behavioral and bio-psycho-social risk factors, and capitalizing on the continuum between risk stratifcation and early, personalized supportive care delivery, innovative models of cancer survivorship care have great potential to enhance survivors' health outcomes and quality of life.
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spelling doaj-art-075147d9ea9e415bb574f64dfe1f80f52025-08-20T02:39:35ZengEdisciencesJournal of Cancer Rehabilitation2704-64942024-12-017414414710.48252/JCR109BEHAVIORAL AND BIO-PSYCHO-SOCIAL FACTORS IN CANCER SURVIVORSHIPAntonino Di Meglio0Cancer Survivorship Program, INSERM U981 – Gustave Roussy, Villejuif, FranceThe incidence of cancer continues to rise, with over 26 million cancer survivors projected by 2040. As survival rates improve, attention must shift toward comprehensively addressing the needs of cancer survivors, not only including prevention of cancer recurrence, but also extending to surveillance and management of physical and psychosocial effects. However, current practices reveal suboptimal engagement in key survivorship services such as health promotion as well as in management of long-term treatment-related symptoms, which can signifcantly impact survivors' quality of life, and also affect medication adherence and, ultimately, clinical outcomes. Predisposition to clinically meaningful symptom burden after cancer and cancer-related frailty represents signifcant risks for a substantial portion of cancer survivors and such risks seem to be driven by multiple individual factors such as age, comorbidities, lifestyle, psycho-social traits, baseline symptom burden pre-treatment, and type of treatment received. An additional important role seem to be played by susceptibility to cancer- induced infammation and accelerated aging. Emerging bio-behavioral models can now help identify patients at higher risk of long-term effects. Interventions targeting modifable factors, like excess weight, poor diet, inactivity, and stress, can address risk factors, and some of them act through mitigation of systemic infammation. Many of these behavioral interventions are multi-target and can also be delivered digitally and/or self-administered. Moving forward, by leveraging knowledge of behavioral and bio-psycho-social risk factors, and capitalizing on the continuum between risk stratifcation and early, personalized supportive care delivery, innovative models of cancer survivorship care have great potential to enhance survivors' health outcomes and quality of life.https://www.edisciences.org/vol-7-issue-4-special-issue-jcr-ottobre-24-behavioral-and-bio-psycho-social-factorssymptomsbehavioral interventions
spellingShingle Antonino Di Meglio
BEHAVIORAL AND BIO-PSYCHO-SOCIAL FACTORS IN CANCER SURVIVORSHIP
Journal of Cancer Rehabilitation
symptoms
behavioral interventions
title BEHAVIORAL AND BIO-PSYCHO-SOCIAL FACTORS IN CANCER SURVIVORSHIP
title_full BEHAVIORAL AND BIO-PSYCHO-SOCIAL FACTORS IN CANCER SURVIVORSHIP
title_fullStr BEHAVIORAL AND BIO-PSYCHO-SOCIAL FACTORS IN CANCER SURVIVORSHIP
title_full_unstemmed BEHAVIORAL AND BIO-PSYCHO-SOCIAL FACTORS IN CANCER SURVIVORSHIP
title_short BEHAVIORAL AND BIO-PSYCHO-SOCIAL FACTORS IN CANCER SURVIVORSHIP
title_sort behavioral and bio psycho social factors in cancer survivorship
topic symptoms
behavioral interventions
url https://www.edisciences.org/vol-7-issue-4-special-issue-jcr-ottobre-24-behavioral-and-bio-psycho-social-factors
work_keys_str_mv AT antoninodimeglio behavioralandbiopsychosocialfactorsincancersurvivorship