Research progress and application prospects of animal models of group B Coxsackievirus infections
Group B Coxsackieviruses (CVBs) consist of six serotypes, CVB1 to CVB6, which can clinically affect the heart, brain, liver, pancreas and other organs, causing myocarditis, encephalitis, myelitis, pancreatitis, hand-foot-and-mouth disease (HFMD) and other diseases, and can even lead to death. CVBs a...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2025-12-01
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| Series: | Emerging Microbes and Infections |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/22221751.2024.2441391 |
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| author | Shihan Weng Rui Zhu Yuanyuan Wu Ningshao Xia Longfa Xu Tong Cheng |
| author_facet | Shihan Weng Rui Zhu Yuanyuan Wu Ningshao Xia Longfa Xu Tong Cheng |
| author_sort | Shihan Weng |
| collection | DOAJ |
| description | Group B Coxsackieviruses (CVBs) consist of six serotypes, CVB1 to CVB6, which can clinically affect the heart, brain, liver, pancreas and other organs, causing myocarditis, encephalitis, myelitis, pancreatitis, hand-foot-and-mouth disease (HFMD) and other diseases, and can even lead to death. CVBs are widespread globally and highly contagious. However, there are currently no approved CVB vaccines or effective treatments. The construction and optimization of animal models will aid in the in-depth understanding of CVB infections and its pathogenesis, providing essential tools for the exploration of vaccine development and antiviral therapies. This paper reviews the latest research progress and application prospects of CVB animal models. |
| format | Article |
| id | doaj-art-074f396385884ddda136341d93f231ee |
| institution | OA Journals |
| issn | 2222-1751 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Emerging Microbes and Infections |
| spelling | doaj-art-074f396385884ddda136341d93f231ee2025-08-20T02:32:04ZengTaylor & Francis GroupEmerging Microbes and Infections2222-17512025-12-0114110.1080/22221751.2024.2441391Research progress and application prospects of animal models of group B Coxsackievirus infectionsShihan Weng0Rui Zhu1Yuanyuan Wu2Ningshao Xia3Longfa Xu4Tong Cheng5State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, School of Life Sciences, School of Public Health, Xiamen University, Xiamen, People’s Republic of ChinaState Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, School of Life Sciences, School of Public Health, Xiamen University, Xiamen, People’s Republic of ChinaState Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, School of Life Sciences, School of Public Health, Xiamen University, Xiamen, People’s Republic of ChinaState Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, School of Life Sciences, School of Public Health, Xiamen University, Xiamen, People’s Republic of ChinaState Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, School of Life Sciences, School of Public Health, Xiamen University, Xiamen, People’s Republic of ChinaState Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, School of Life Sciences, School of Public Health, Xiamen University, Xiamen, People’s Republic of ChinaGroup B Coxsackieviruses (CVBs) consist of six serotypes, CVB1 to CVB6, which can clinically affect the heart, brain, liver, pancreas and other organs, causing myocarditis, encephalitis, myelitis, pancreatitis, hand-foot-and-mouth disease (HFMD) and other diseases, and can even lead to death. CVBs are widespread globally and highly contagious. However, there are currently no approved CVB vaccines or effective treatments. The construction and optimization of animal models will aid in the in-depth understanding of CVB infections and its pathogenesis, providing essential tools for the exploration of vaccine development and antiviral therapies. This paper reviews the latest research progress and application prospects of CVB animal models.https://www.tandfonline.com/doi/10.1080/22221751.2024.2441391Group B coxsackievirusesinfectious diseaseanimal modelinfectionvaccine and drug research |
| spellingShingle | Shihan Weng Rui Zhu Yuanyuan Wu Ningshao Xia Longfa Xu Tong Cheng Research progress and application prospects of animal models of group B Coxsackievirus infections Emerging Microbes and Infections Group B coxsackieviruses infectious disease animal model infection vaccine and drug research |
| title | Research progress and application prospects of animal models of group B Coxsackievirus infections |
| title_full | Research progress and application prospects of animal models of group B Coxsackievirus infections |
| title_fullStr | Research progress and application prospects of animal models of group B Coxsackievirus infections |
| title_full_unstemmed | Research progress and application prospects of animal models of group B Coxsackievirus infections |
| title_short | Research progress and application prospects of animal models of group B Coxsackievirus infections |
| title_sort | research progress and application prospects of animal models of group b coxsackievirus infections |
| topic | Group B coxsackieviruses infectious disease animal model infection vaccine and drug research |
| url | https://www.tandfonline.com/doi/10.1080/22221751.2024.2441391 |
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