A comprehensive review on the pretreatment and detection methods of nitrofurans and their metabolites in animal-derived food and environmental samples

In recent years, the residues of nitrofurans (NFs) and their metabolites in animal-derived food and environmental samples have gained widespread attention. The parent drugs and their metabolites have displayed significant toxicity to human health including carcinogenic, mutagenic and teratogenic eff...

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Main Authors: Xiaoling Zheng, Yong Xie, Zhuoer Chen, Mingdong Cao, Xianlu Lei, Tao Le
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Food Chemistry: X
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Online Access:http://www.sciencedirect.com/science/article/pii/S2590157524008162
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author Xiaoling Zheng
Yong Xie
Zhuoer Chen
Mingdong Cao
Xianlu Lei
Tao Le
author_facet Xiaoling Zheng
Yong Xie
Zhuoer Chen
Mingdong Cao
Xianlu Lei
Tao Le
author_sort Xiaoling Zheng
collection DOAJ
description In recent years, the residues of nitrofurans (NFs) and their metabolites in animal-derived food and environmental samples have gained widespread attention. The parent drugs and their metabolites have displayed significant toxicity to human health including carcinogenic, mutagenic and teratogenic effects, leading to banned in animal husbandry in many countries. Hence, monitoring the residues of NFs is necessary to guarantee public health and ecological security. This review aims to summarize and assess the structural properties, residue status, sample pretreatment methods (liquid-liquid extraction, solid-phase extraction, Quick, Easy, Cheap, Effective, Rugged, and Safe (QuEChERS), and field-assisted extraction), and detection methods (chromatographic analysis, immunoassay, and some innovative detection methods) for NFs and their metabolites in animal-derived food and environmental samples. This paper provides a detailed reference and discussion for the analysis of NFs and their metabolites, which can effectively promote the establishment of innovative detection methods for NFs and their metabolites residues.
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issn 2590-1575
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publishDate 2024-12-01
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series Food Chemistry: X
spelling doaj-art-074d692377794139be27dc90fe5afeba2025-08-20T01:59:34ZengElsevierFood Chemistry: X2590-15752024-12-012410192810.1016/j.fochx.2024.101928A comprehensive review on the pretreatment and detection methods of nitrofurans and their metabolites in animal-derived food and environmental samplesXiaoling Zheng0Yong Xie1Zhuoer Chen2Mingdong Cao3Xianlu Lei4Tao Le5Chongqing Key Laboratory of Conservation and Utilization of Freshwater Fishes, Animal Biology Key Laboratory of Chongqing Education Commission of China, College of Life Sciences, Chongqing Normal University, Chongqing 401331, ChinaBioassay 3D Reconstruction Laboratory, Chongqing Polytechnic University of Electronic Technology, Chongqing 401331, ChinaChongqing Key Laboratory of Conservation and Utilization of Freshwater Fishes, Animal Biology Key Laboratory of Chongqing Education Commission of China, College of Life Sciences, Chongqing Normal University, Chongqing 401331, ChinaChongqing Key Laboratory of Conservation and Utilization of Freshwater Fishes, Animal Biology Key Laboratory of Chongqing Education Commission of China, College of Life Sciences, Chongqing Normal University, Chongqing 401331, ChinaChongqing Key Laboratory of Conservation and Utilization of Freshwater Fishes, Animal Biology Key Laboratory of Chongqing Education Commission of China, College of Life Sciences, Chongqing Normal University, Chongqing 401331, ChinaChongqing Key Laboratory of Conservation and Utilization of Freshwater Fishes, Animal Biology Key Laboratory of Chongqing Education Commission of China, College of Life Sciences, Chongqing Normal University, Chongqing 401331, China; Corresponding author.In recent years, the residues of nitrofurans (NFs) and their metabolites in animal-derived food and environmental samples have gained widespread attention. The parent drugs and their metabolites have displayed significant toxicity to human health including carcinogenic, mutagenic and teratogenic effects, leading to banned in animal husbandry in many countries. Hence, monitoring the residues of NFs is necessary to guarantee public health and ecological security. This review aims to summarize and assess the structural properties, residue status, sample pretreatment methods (liquid-liquid extraction, solid-phase extraction, Quick, Easy, Cheap, Effective, Rugged, and Safe (QuEChERS), and field-assisted extraction), and detection methods (chromatographic analysis, immunoassay, and some innovative detection methods) for NFs and their metabolites in animal-derived food and environmental samples. This paper provides a detailed reference and discussion for the analysis of NFs and their metabolites, which can effectively promote the establishment of innovative detection methods for NFs and their metabolites residues.http://www.sciencedirect.com/science/article/pii/S2590157524008162NitrofuransMetabolitesSample pretreatmentDetection technology
spellingShingle Xiaoling Zheng
Yong Xie
Zhuoer Chen
Mingdong Cao
Xianlu Lei
Tao Le
A comprehensive review on the pretreatment and detection methods of nitrofurans and their metabolites in animal-derived food and environmental samples
Food Chemistry: X
Nitrofurans
Metabolites
Sample pretreatment
Detection technology
title A comprehensive review on the pretreatment and detection methods of nitrofurans and their metabolites in animal-derived food and environmental samples
title_full A comprehensive review on the pretreatment and detection methods of nitrofurans and their metabolites in animal-derived food and environmental samples
title_fullStr A comprehensive review on the pretreatment and detection methods of nitrofurans and their metabolites in animal-derived food and environmental samples
title_full_unstemmed A comprehensive review on the pretreatment and detection methods of nitrofurans and their metabolites in animal-derived food and environmental samples
title_short A comprehensive review on the pretreatment and detection methods of nitrofurans and their metabolites in animal-derived food and environmental samples
title_sort comprehensive review on the pretreatment and detection methods of nitrofurans and their metabolites in animal derived food and environmental samples
topic Nitrofurans
Metabolites
Sample pretreatment
Detection technology
url http://www.sciencedirect.com/science/article/pii/S2590157524008162
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