Cinnamic acid alleviates hypertensive left ventricular hypertrophy by antagonizing the vasopressor activity and the pro-cardiac hypertrophic signaling of angiotensin II

Cinnamic acid alleviates hypertensive left ventricular hypertrophy by antagonizing the vasopressor activity and the pro-cardiac hypertrophic signaling of angiotensin II

BackgroundHypertension is the most common cause of pathological left ventricular hypertrophy, a condition causally associated with debilitating heart failure and cardiovascular events in hypertensive patients. It is well recognized that the disease burden of hypertension-linked heart failure remains...

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Bibliographic Details
Main Authors: Yimeng Cui, Yawei Yang, Xinmiao Tang, Peiwei Wang, Jingang Cui, Yu Chen, Teng Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Pharmacology
Subjects:
cinnamic acid
hypertension
left ventricular hypertrophy
cardiomyocytes
angiotensin II
pro-hypertrophic responses
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1555991/full
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