Detection of Crimean-Congo Haemorrhagic Fever virus antibodies in cattle in Kenedougou and Mouhoun provinces in Burkina Faso

Background: Crimean-Congo haemorrhagic Fever (CCHF) is a zoonotic disease caused by an Orthonairovirus of the Nairoviridae family transmitted by tick bites and also contact with infected blood, tissues or body fluids. Until now, fewer studies have been conducted in animals in Burkina Faso. Aim: T...

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Main Authors: Laibane Dieudonne Dahourou, Madi Savadogo, Mikhailou Kiswend-sida Dera, Lamoussa Roland Abga, Bruno Lalidia Ouoba, Rayangnewênde Stephane Arnaud Tapsoba, Bernadette Yougbare, Salimata Akio, Lamouni Habibata Zerbo, Amadou Traore, Rianatou Bada Alambedji
Format: Article
Language:English
Published: Tripoli University 2024-08-01
Series:Open Veterinary Journal
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Online Access:https://www.openveterinaryjournal.com/?mno=199973
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author Laibane Dieudonne Dahourou
Madi Savadogo
Mikhailou Kiswend-sida Dera
Lamoussa Roland Abga
Bruno Lalidia Ouoba
Rayangnewênde Stephane Arnaud Tapsoba
Bernadette Yougbare
Salimata Akio
Lamouni Habibata Zerbo
Amadou Traore
Rianatou Bada Alambedji
author_facet Laibane Dieudonne Dahourou
Madi Savadogo
Mikhailou Kiswend-sida Dera
Lamoussa Roland Abga
Bruno Lalidia Ouoba
Rayangnewênde Stephane Arnaud Tapsoba
Bernadette Yougbare
Salimata Akio
Lamouni Habibata Zerbo
Amadou Traore
Rianatou Bada Alambedji
author_sort Laibane Dieudonne Dahourou
collection DOAJ
description Background: Crimean-Congo haemorrhagic Fever (CCHF) is a zoonotic disease caused by an Orthonairovirus of the Nairoviridae family transmitted by tick bites and also contact with infected blood, tissues or body fluids. Until now, fewer studies have been conducted in animals in Burkina Faso. Aim: This study was conducted to investigate the seroprevalence and risk factors of CCHF in two provinces of Burkina Faso. Methods: Serum samples were collected from 371 bovine animals. In addition, questionnaire surveys were performed with cattle breeders. The double-antigen sandwich ELISA test was used to determine the presence of antibodies against the CCHF virus in serum samples. Results: The results showed an overall prevalence of 72.2% (95% CI: 67.6% - 76.7%). Within the 74 herds included in the study a herd prevalence of 96% (95% CI: 91.4% - 100%) was obtained. The prevalence was significantly higher in Mouhoun province (80%, 95% CI: 74% - 86%) compared to Kenedougou province (65.6%, 95% CI: 59.1% -72.2%). Multivariable regression analysis showed that females were more likely to be infected (OR=1.99, 95% CI: 1.1-3.6, p=0.023) than males. In addition, cross-breed animals (OR= 6.42, 95% CI: 1.71-24.14, p=0.006) were more likely to be infected compared to local-bred animals. This study revealed the presence of antibodies of CCHF virus in cattle in the study area, indicating the need of implementing control measures in veterinary sector. Conclusion: Despite the importance of CCHF in public health, no study has been implemented regarding this condition in animal in Burkina Faso. This study described evidence of cattle exposure to the virus in Burkina Faso. [Open Vet J 2024; 14(8.000): 1912-1920]
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spelling doaj-art-0746ef8ce23b4142b6a397361b864a9e2025-08-20T01:47:36ZengTripoli UniversityOpen Veterinary Journal2226-44852218-60502024-08-011481912192010.5455/OVJ.2024.v14.i8.19199973Detection of Crimean-Congo Haemorrhagic Fever virus antibodies in cattle in Kenedougou and Mouhoun provinces in Burkina FasoLaibane Dieudonne Dahourou0Madi Savadogo1Mikhailou Kiswend-sida Dera2Lamoussa Roland Abga3Bruno Lalidia Ouoba4Rayangnewênde Stephane Arnaud Tapsoba5Bernadette Yougbare6Salimata Akio7Lamouni Habibata Zerbo8Amadou Traore9Rianatou Bada Alambedji10Po Box176 Dedougou Po box 7047, Ouagadougou Po box 1087, Bobo-Dioulasso Po Box 5077, Dakar Po box 7026 Ouagadougou Po Box 476, Ouagadougou Po Box 476, Ouagadougou Po Box 5077, Dakar Po box 7026 Ouagadougou Po Box 476, Ouagadougou Po Box 5077, DakarBackground: Crimean-Congo haemorrhagic Fever (CCHF) is a zoonotic disease caused by an Orthonairovirus of the Nairoviridae family transmitted by tick bites and also contact with infected blood, tissues or body fluids. Until now, fewer studies have been conducted in animals in Burkina Faso. Aim: This study was conducted to investigate the seroprevalence and risk factors of CCHF in two provinces of Burkina Faso. Methods: Serum samples were collected from 371 bovine animals. In addition, questionnaire surveys were performed with cattle breeders. The double-antigen sandwich ELISA test was used to determine the presence of antibodies against the CCHF virus in serum samples. Results: The results showed an overall prevalence of 72.2% (95% CI: 67.6% - 76.7%). Within the 74 herds included in the study a herd prevalence of 96% (95% CI: 91.4% - 100%) was obtained. The prevalence was significantly higher in Mouhoun province (80%, 95% CI: 74% - 86%) compared to Kenedougou province (65.6%, 95% CI: 59.1% -72.2%). Multivariable regression analysis showed that females were more likely to be infected (OR=1.99, 95% CI: 1.1-3.6, p=0.023) than males. In addition, cross-breed animals (OR= 6.42, 95% CI: 1.71-24.14, p=0.006) were more likely to be infected compared to local-bred animals. This study revealed the presence of antibodies of CCHF virus in cattle in the study area, indicating the need of implementing control measures in veterinary sector. Conclusion: Despite the importance of CCHF in public health, no study has been implemented regarding this condition in animal in Burkina Faso. This study described evidence of cattle exposure to the virus in Burkina Faso. [Open Vet J 2024; 14(8.000): 1912-1920]https://www.openveterinaryjournal.com/?mno=199973burkina fasocattlehaemorrhagic fever viruscrimean-congoseroepidemiologic studies
spellingShingle Laibane Dieudonne Dahourou
Madi Savadogo
Mikhailou Kiswend-sida Dera
Lamoussa Roland Abga
Bruno Lalidia Ouoba
Rayangnewênde Stephane Arnaud Tapsoba
Bernadette Yougbare
Salimata Akio
Lamouni Habibata Zerbo
Amadou Traore
Rianatou Bada Alambedji
Detection of Crimean-Congo Haemorrhagic Fever virus antibodies in cattle in Kenedougou and Mouhoun provinces in Burkina Faso
Open Veterinary Journal
burkina faso
cattle
haemorrhagic fever virus
crimean-congo
seroepidemiologic studies
title Detection of Crimean-Congo Haemorrhagic Fever virus antibodies in cattle in Kenedougou and Mouhoun provinces in Burkina Faso
title_full Detection of Crimean-Congo Haemorrhagic Fever virus antibodies in cattle in Kenedougou and Mouhoun provinces in Burkina Faso
title_fullStr Detection of Crimean-Congo Haemorrhagic Fever virus antibodies in cattle in Kenedougou and Mouhoun provinces in Burkina Faso
title_full_unstemmed Detection of Crimean-Congo Haemorrhagic Fever virus antibodies in cattle in Kenedougou and Mouhoun provinces in Burkina Faso
title_short Detection of Crimean-Congo Haemorrhagic Fever virus antibodies in cattle in Kenedougou and Mouhoun provinces in Burkina Faso
title_sort detection of crimean congo haemorrhagic fever virus antibodies in cattle in kenedougou and mouhoun provinces in burkina faso
topic burkina faso
cattle
haemorrhagic fever virus
crimean-congo
seroepidemiologic studies
url https://www.openveterinaryjournal.com/?mno=199973
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