Differential Reponses of Hematopoietic Stem and Progenitor Cells to mTOR Inhibition
Abnormal activation of the mammalian target of rapamycin (mTOR) signaling pathway has been observed in a variety of human cancers. Therefore, targeting of the mTOR pathway is an attractive strategy for cancer treatment and several mTOR inhibitors, including AZD8055 (AZD), a novel dual mTORC1/2 inhib...
Saved in:
Main Authors: | Aimin Yang, Xia Xiao, Mingfeng Zhao, Amanda C. LaRue, Bradley A. Schulte, Gavin Y. Wang |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2015-01-01
|
Series: | Stem Cells International |
Online Access: | http://dx.doi.org/10.1155/2015/561404 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
mTOR Inhibition: From Aging to Autism and Beyond
by: Matt Kaeberlein
Published: (2013-01-01) -
Beneficial Effects of Resveratrol-Mediated Inhibition of the mTOR Pathway in Spinal Cord Injury
by: Jingying Zhou, et al.
Published: (2018-01-01) -
Baicalein induces apoptosis by inhibiting the glutamine-mTOR metabolic pathway in lung cancer
by: Jingyang Li, et al.
Published: (2025-02-01) -
Gastric Cancer Mesenchymal Stem Cells Inhibit NK Cell Function through mTOR Signalling to Promote Tumour Growth
by: Shuwei Guo, et al.
Published: (2021-01-01) -
Alcohol Inhibits Odontogenic Differentiation of Human Dental Pulp Cells by Activating mTOR Signaling
by: Wei Qin, et al.
Published: (2017-01-01)