Abandoning presumptive antimalarial treatment for febrile children aged less than five years--a case of running before we can walk?
<h4>Background to the debate</h4>Current guidelines recommend that all fever episodes in African children be treated presumptively with antimalarial drugs. But declining malarial transmission in parts of sub-Saharan Africa, declining proportions of fevers due to malaria, and the availabi...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-01-01
|
| Series: | PLoS Medicine |
| Online Access: | https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1000015&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850183507316310016 |
|---|---|
| author | Mike English Hugh Reyburn Catherine Goodman Robert W Snow |
| author_facet | Mike English Hugh Reyburn Catherine Goodman Robert W Snow |
| author_sort | Mike English |
| collection | DOAJ |
| description | <h4>Background to the debate</h4>Current guidelines recommend that all fever episodes in African children be treated presumptively with antimalarial drugs. But declining malarial transmission in parts of sub-Saharan Africa, declining proportions of fevers due to malaria, and the availability of rapid diagnostic tests mean it may be time for this policy to change. This debate examines whether enough evidence exists to support abandoning presumptive treatment and whether African health systems have the capacity to support a shift toward laboratory-confirmed rather than presumptive diagnosis and treatment of malaria in children under five. |
| format | Article |
| id | doaj-art-07313dacf3b04873be5ba5537562cd6a |
| institution | OA Journals |
| issn | 1549-1277 1549-1676 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS Medicine |
| spelling | doaj-art-07313dacf3b04873be5ba5537562cd6a2025-08-20T02:17:20ZengPublic Library of Science (PLoS)PLoS Medicine1549-12771549-16762009-01-0161e100001510.1371/journal.pmed.1000015Abandoning presumptive antimalarial treatment for febrile children aged less than five years--a case of running before we can walk?Mike EnglishHugh ReyburnCatherine GoodmanRobert W Snow<h4>Background to the debate</h4>Current guidelines recommend that all fever episodes in African children be treated presumptively with antimalarial drugs. But declining malarial transmission in parts of sub-Saharan Africa, declining proportions of fevers due to malaria, and the availability of rapid diagnostic tests mean it may be time for this policy to change. This debate examines whether enough evidence exists to support abandoning presumptive treatment and whether African health systems have the capacity to support a shift toward laboratory-confirmed rather than presumptive diagnosis and treatment of malaria in children under five.https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1000015&type=printable |
| spellingShingle | Mike English Hugh Reyburn Catherine Goodman Robert W Snow Abandoning presumptive antimalarial treatment for febrile children aged less than five years--a case of running before we can walk? PLoS Medicine |
| title | Abandoning presumptive antimalarial treatment for febrile children aged less than five years--a case of running before we can walk? |
| title_full | Abandoning presumptive antimalarial treatment for febrile children aged less than five years--a case of running before we can walk? |
| title_fullStr | Abandoning presumptive antimalarial treatment for febrile children aged less than five years--a case of running before we can walk? |
| title_full_unstemmed | Abandoning presumptive antimalarial treatment for febrile children aged less than five years--a case of running before we can walk? |
| title_short | Abandoning presumptive antimalarial treatment for febrile children aged less than five years--a case of running before we can walk? |
| title_sort | abandoning presumptive antimalarial treatment for febrile children aged less than five years a case of running before we can walk |
| url | https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1000015&type=printable |
| work_keys_str_mv | AT mikeenglish abandoningpresumptiveantimalarialtreatmentforfebrilechildrenagedlessthanfiveyearsacaseofrunningbeforewecanwalk AT hughreyburn abandoningpresumptiveantimalarialtreatmentforfebrilechildrenagedlessthanfiveyearsacaseofrunningbeforewecanwalk AT catherinegoodman abandoningpresumptiveantimalarialtreatmentforfebrilechildrenagedlessthanfiveyearsacaseofrunningbeforewecanwalk AT robertwsnow abandoningpresumptiveantimalarialtreatmentforfebrilechildrenagedlessthanfiveyearsacaseofrunningbeforewecanwalk |