Urological Complications of Hirschsprung-Related Crohn’s Disease: A Case Report
Hirschsprung disease (HSCR) is a rare congenital intestinal disease characterized by the absence of ganglion cells in the myenteric and submucosal plexuses of the intestine. Individuals with HSCR demonstrate a higher risk for inflammatory bowel disease (IBD), with Chron’s disease (CD) commonly obser...
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| Format: | Article |
| Language: | English |
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Interna Publishing
2025-01-01
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| Series: | Acta Medica Indonesiana |
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| Online Access: | https://actamedindones.org/index.php/ijim/article/view/2868 |
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| author | Kartika Anastasia Kosasih Saut Horas Hatoguan Nababan Andrian Setiabakti |
| author_facet | Kartika Anastasia Kosasih Saut Horas Hatoguan Nababan Andrian Setiabakti |
| author_sort | Kartika Anastasia Kosasih |
| collection | DOAJ |
| description | Hirschsprung disease (HSCR) is a rare congenital intestinal disease characterized by the absence of ganglion cells in the myenteric and submucosal plexuses of the intestine. Individuals with HSCR demonstrate a higher risk for inflammatory bowel disease (IBD), with Chron’s disease (CD) commonly observed. Renal and urinary involvement is reported by between 4 and 23% of IBD patients, which manifests as urinary calculi, fistulas, and ureteral obstruction, which causes hydronephrosis. Those conditions can lead to a predisposition to recurrent urinary tract infections (UTIs) and should be suspected in male patients with IBD. A 26-year-old male with a history of HSCR and multiple surgeries presented with recurrent UTIs over 3 months. Upon further evaluation, he was found to have hydronephrosis in both kidneys. An MRI of the abdomen with contrast showed thickening and fibrosis in contact with the posterior wall of the rectum, causing a narrowing of the bilateral ureter. This clinical case has been reported to raise awareness of urological complications in CD patients with a history of HSCR, with recurrent UTIs as the presenting symptom. |
| format | Article |
| id | doaj-art-072dd591579e4eb0b22831a26e169e60 |
| institution | DOAJ |
| issn | 0125-9326 2338-2732 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Interna Publishing |
| record_format | Article |
| series | Acta Medica Indonesiana |
| spelling | doaj-art-072dd591579e4eb0b22831a26e169e602025-08-20T03:10:21ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322025-01-01571721Urological Complications of Hirschsprung-Related Crohn’s Disease: A Case ReportKartika Anastasia Kosasih0Saut Horas Hatoguan Nababan1Andrian Setiabakti2Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, IndonesiaDivision of Hepato-biliary, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo Hospital, Jakarta, IndonesiaDepartment of Internal Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, IndonesiaHirschsprung disease (HSCR) is a rare congenital intestinal disease characterized by the absence of ganglion cells in the myenteric and submucosal plexuses of the intestine. Individuals with HSCR demonstrate a higher risk for inflammatory bowel disease (IBD), with Chron’s disease (CD) commonly observed. Renal and urinary involvement is reported by between 4 and 23% of IBD patients, which manifests as urinary calculi, fistulas, and ureteral obstruction, which causes hydronephrosis. Those conditions can lead to a predisposition to recurrent urinary tract infections (UTIs) and should be suspected in male patients with IBD. A 26-year-old male with a history of HSCR and multiple surgeries presented with recurrent UTIs over 3 months. Upon further evaluation, he was found to have hydronephrosis in both kidneys. An MRI of the abdomen with contrast showed thickening and fibrosis in contact with the posterior wall of the rectum, causing a narrowing of the bilateral ureter. This clinical case has been reported to raise awareness of urological complications in CD patients with a history of HSCR, with recurrent UTIs as the presenting symptom.https://actamedindones.org/index.php/ijim/article/view/2868chron’s diseasehirschsprung diseasehydronephrosisureteral obstruction |
| spellingShingle | Kartika Anastasia Kosasih Saut Horas Hatoguan Nababan Andrian Setiabakti Urological Complications of Hirschsprung-Related Crohn’s Disease: A Case Report Acta Medica Indonesiana chron’s disease hirschsprung disease hydronephrosis ureteral obstruction |
| title | Urological Complications of Hirschsprung-Related Crohn’s Disease: A Case Report |
| title_full | Urological Complications of Hirschsprung-Related Crohn’s Disease: A Case Report |
| title_fullStr | Urological Complications of Hirschsprung-Related Crohn’s Disease: A Case Report |
| title_full_unstemmed | Urological Complications of Hirschsprung-Related Crohn’s Disease: A Case Report |
| title_short | Urological Complications of Hirschsprung-Related Crohn’s Disease: A Case Report |
| title_sort | urological complications of hirschsprung related crohn s disease a case report |
| topic | chron’s disease hirschsprung disease hydronephrosis ureteral obstruction |
| url | https://actamedindones.org/index.php/ijim/article/view/2868 |
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