Integrating Mendelian randomization and multi-transcriptomic analyses to unveil the genetic association risk of regulatory T cell-mediated free cholesterol and gastric cancer
Abstract Background Evidence from observational studies suggests an association between free cholesterol and gastric cancer. Immune cells play a crucial role in the tumor microenvironment of gastric cancer, and free cholesterol can influence immune cells in various ways, thereby impacting gastric ca...
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| Main Authors: | Fanyu Peng, Haitao Liu, Yesong Guo, Jing Wen, Yizhi Ge, Yanhong Luo |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-05-01
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| Series: | Discover Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s12672-025-02739-1 |
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