SERCA-mediated endoplasmic reticulum stress facilitates hematopoietic stem cell mobilization

SERCA-mediated endoplasmic reticulum stress facilitates hematopoietic stem cell mobilization

Abstract Background Hematopoietic stem cell (HSC) transplantation is widely recognized as an effective treatment for various malignant diseases. Enhancing HSC mobilization can improve transplantation outcomes and ultimately increase patient survival rates. Recent studies suggest that mild endoplasmi...

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Bibliographic Details
Main Authors: Lijun Li, Danhua Xu, Xinxin Huang
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Stem Cell Research & Therapy
Subjects:
ER stress
SERCA
HSC
Mobilization
CXCR4
Online Access:https://doi.org/10.1186/s13287-025-04345-y
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