Size distribution of extracellular vesicles in pretreatment ascites and plasma is correlated with primary treatment outcome in advanced high-grade serous carcinoma

Size distribution of extracellular vesicles in pretreatment ascites and plasma is correlated with primary treatment outcome in advanced high-grade serous carcinoma

Abstract To improve the treatment outcome and survival of patients with advanced high-grade serous carcinoma (HGSC), prognostic biomarkers for assessing the feasibility of complete (R0) or optimal (R1) primary cytoreductive surgery are needed. Additionally, biomarkers for predicting the response to...

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Bibliographic Details
Main Authors: Maruša Herzog, Ivan Verdenik, Borut Kobal, Katarina Černe
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
High-grade serous carcinoma
Extracellular vesicles
Biomarkers
Nanoparticle tracking analysis
Resection success
Chemotherapy response
Online Access:https://doi.org/10.1038/s41598-025-88707-9
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https://doi.org/10.1038/s41598-025-88707-9

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