Shaping the future of microwave tumor ablation: a new direction in precision and control of device performance

Microwave ablation (MWA) is becoming an increasingly important minimally invasive treatment option for localized tumors in many organ systems due to recent advancements in microwave technology that have conferred many advantages over other tumor ablation modalities. Despite these improvements in tec...

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Main Authors: Austin Pfannenstiel, Jason Iannuccilli, Francois H. Cornelis, Damian E. Dupuy, Warren L. Beard, Punit Prakash
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:International Journal of Hyperthermia
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Online Access:https://www.tandfonline.com/doi/10.1080/02656736.2021.1991012
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author Austin Pfannenstiel
Jason Iannuccilli
Francois H. Cornelis
Damian E. Dupuy
Warren L. Beard
Punit Prakash
author_facet Austin Pfannenstiel
Jason Iannuccilli
Francois H. Cornelis
Damian E. Dupuy
Warren L. Beard
Punit Prakash
author_sort Austin Pfannenstiel
collection DOAJ
description Microwave ablation (MWA) is becoming an increasingly important minimally invasive treatment option for localized tumors in many organ systems due to recent advancements in microwave technology that have conferred many advantages over other tumor ablation modalities. Despite these improvements in technology and development of applicators for site-specific tumor applications, the vast majority of commercially available MWA applicators are generally designed to create large-volume, symmetric, ellipsoid or spherically-shaped treatment zones and often lack the consistency, predictability, and spatial control needed to treat tumor targets near critical structures that are vulnerable to inadvertent thermal injury. The relatively new development and ongoing translation of directional microwave ablation (DMWA) technology, however, has the potential to confer an added level of control over the treatment zone shape relative to applicator position, and shows great promise to expand MWA’s clinical applicability in treating tumors in challenging locations. This paper presents a review of the industry-standard commercially available MWA technology, its clinical applications, and its limitations when used for minimally-invasive tumor treatment in medical practice followed by discussion of new advancements in experimental directional microwave ablation (DMWA) technology, various techniques and approaches to its use, and examples of how this technology may be used to treat tumors in challenging locations that may otherwise preclude safe treatment by conventional omni-directional MWA devices.
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spelling doaj-art-0720907ff3424bd796e3b97946cb4dfb2025-08-20T02:40:36ZengTaylor & Francis GroupInternational Journal of Hyperthermia0265-67361464-51572022-12-0139166467410.1080/02656736.2021.1991012Shaping the future of microwave tumor ablation: a new direction in precision and control of device performanceAustin Pfannenstiel0Jason Iannuccilli1Francois H. Cornelis2Damian E. Dupuy3Warren L. Beard4Punit Prakash5Precision Microwave Inc, Manhattan, KS, USADepartment of Diagnostic Imaging, Division of Interventional Oncology, Rhode Island Hospital, Providence, RI, USAInterventional Radiology Service, Memorial Sloan Kettering Cancer Center, NY, USADiagnostic Imaging, Brown University, Radiology, Cape Cod Hospital, MA, USADepartment of Clinical Sciences, Kansas State University, Manhattan, KS, USADepartment of Electrical and Computer Engineering, Kansas State University, Manhattan, KS, USAMicrowave ablation (MWA) is becoming an increasingly important minimally invasive treatment option for localized tumors in many organ systems due to recent advancements in microwave technology that have conferred many advantages over other tumor ablation modalities. Despite these improvements in technology and development of applicators for site-specific tumor applications, the vast majority of commercially available MWA applicators are generally designed to create large-volume, symmetric, ellipsoid or spherically-shaped treatment zones and often lack the consistency, predictability, and spatial control needed to treat tumor targets near critical structures that are vulnerable to inadvertent thermal injury. The relatively new development and ongoing translation of directional microwave ablation (DMWA) technology, however, has the potential to confer an added level of control over the treatment zone shape relative to applicator position, and shows great promise to expand MWA’s clinical applicability in treating tumors in challenging locations. This paper presents a review of the industry-standard commercially available MWA technology, its clinical applications, and its limitations when used for minimally-invasive tumor treatment in medical practice followed by discussion of new advancements in experimental directional microwave ablation (DMWA) technology, various techniques and approaches to its use, and examples of how this technology may be used to treat tumors in challenging locations that may otherwise preclude safe treatment by conventional omni-directional MWA devices.https://www.tandfonline.com/doi/10.1080/02656736.2021.1991012Microwave ablationthermal ablationimage-guided therapydirectional antenna
spellingShingle Austin Pfannenstiel
Jason Iannuccilli
Francois H. Cornelis
Damian E. Dupuy
Warren L. Beard
Punit Prakash
Shaping the future of microwave tumor ablation: a new direction in precision and control of device performance
International Journal of Hyperthermia
Microwave ablation
thermal ablation
image-guided therapy
directional antenna
title Shaping the future of microwave tumor ablation: a new direction in precision and control of device performance
title_full Shaping the future of microwave tumor ablation: a new direction in precision and control of device performance
title_fullStr Shaping the future of microwave tumor ablation: a new direction in precision and control of device performance
title_full_unstemmed Shaping the future of microwave tumor ablation: a new direction in precision and control of device performance
title_short Shaping the future of microwave tumor ablation: a new direction in precision and control of device performance
title_sort shaping the future of microwave tumor ablation a new direction in precision and control of device performance
topic Microwave ablation
thermal ablation
image-guided therapy
directional antenna
url https://www.tandfonline.com/doi/10.1080/02656736.2021.1991012
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