Biomarkers in Skin Mucus for a Minimally Invasive Approach to Stress in Red Tilapia (<i>Oreochromis</i> sp.) Fry

In a context where aquaculture continues to grow, it is essential to understand how culture conditions influence fish stress. The welfare of red tilapia fry (<i>Oreochromis</i> sp.), weighing 0.6 ± 0.3 g and with an initial total length of 3.548 ± 0.285 cm, was evaluated in two culture s...

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Main Authors: Hernán Antonio Alzate-Díaz, Laura Fernández-Alacid, Sandra Clemencia Pardo-Carrasco
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Biology
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Online Access:https://www.mdpi.com/2079-7737/14/2/112
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author Hernán Antonio Alzate-Díaz
Laura Fernández-Alacid
Sandra Clemencia Pardo-Carrasco
author_facet Hernán Antonio Alzate-Díaz
Laura Fernández-Alacid
Sandra Clemencia Pardo-Carrasco
author_sort Hernán Antonio Alzate-Díaz
collection DOAJ
description In a context where aquaculture continues to grow, it is essential to understand how culture conditions influence fish stress. The welfare of red tilapia fry (<i>Oreochromis</i> sp.), weighing 0.6 ± 0.3 g and with an initial total length of 3.548 ± 0.285 cm, was evaluated in two culture systems, biofloc and land-based ponds, over a period of 30 days through biomarkers associated with the skin mucosa, such as protein, glucose, lactate, and the hormone cortisol, in addition to their relationships with protein, seeking a comprehensive view of the physiological state and stress of these fish. Mucus samples were thawed and prepared by mechanical homogenization and centrifugation. The results reveal that the biofloc system provides a more conducive environment for welfare, evidenced by higher mucus protein levels of 1.598 ± 0.733 mg/mL, 2.316 ± 1.01 mg/mL, and 1.203 ± 0.640 mg/mL for culture days 10, 20 and 30, respectively, and lower cortisol > 1 ng/mL and lactate contents 1799 ± 1135 µg/mL, 30,271 ± 24,613 µg/mL, and 21,829 ± 23,507 µg/mL for culture days 10, 20 and 30, respectively, compounds largely associated with animal stress. This highlights the direct relationship between culture, environment and fish health and highlights skin mucus as a valuable minimally invasive biomarker. It is also important to note that improved fish welfare supports fish growth and health and promotes more sustainable aquaculture practices, contributing to more efficient and responsible production in the industry.
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spelling doaj-art-070fd51661014609b8b83044c0e5a25a2025-08-20T03:12:05ZengMDPI AGBiology2079-77372025-01-0114211210.3390/biology14020112Biomarkers in Skin Mucus for a Minimally Invasive Approach to Stress in Red Tilapia (<i>Oreochromis</i> sp.) FryHernán Antonio Alzate-Díaz0Laura Fernández-Alacid1Sandra Clemencia Pardo-Carrasco2Department of Animal Production, Faculty of Agrarian Sciences, Universidad Nacional de Colombia, Medellín Campus, Carrera 65 #59ª-110, Bloque 50 Of. 309 Nucleo El Volador, Medellín 050034, ColombiaDepartment of Cell Biology, Physiology and Immunology, Faculty of Biology, University of Barcelona, Avda. Diagonal 643, 08028 Barcelona, SpainDepartment of Animal Production, Faculty of Agrarian Sciences, Universidad Nacional de Colombia, Medellín Campus, Carrera 65 #59ª-110, Bloque 50 Of. 309 Nucleo El Volador, Medellín 050034, ColombiaIn a context where aquaculture continues to grow, it is essential to understand how culture conditions influence fish stress. The welfare of red tilapia fry (<i>Oreochromis</i> sp.), weighing 0.6 ± 0.3 g and with an initial total length of 3.548 ± 0.285 cm, was evaluated in two culture systems, biofloc and land-based ponds, over a period of 30 days through biomarkers associated with the skin mucosa, such as protein, glucose, lactate, and the hormone cortisol, in addition to their relationships with protein, seeking a comprehensive view of the physiological state and stress of these fish. Mucus samples were thawed and prepared by mechanical homogenization and centrifugation. The results reveal that the biofloc system provides a more conducive environment for welfare, evidenced by higher mucus protein levels of 1.598 ± 0.733 mg/mL, 2.316 ± 1.01 mg/mL, and 1.203 ± 0.640 mg/mL for culture days 10, 20 and 30, respectively, and lower cortisol > 1 ng/mL and lactate contents 1799 ± 1135 µg/mL, 30,271 ± 24,613 µg/mL, and 21,829 ± 23,507 µg/mL for culture days 10, 20 and 30, respectively, compounds largely associated with animal stress. This highlights the direct relationship between culture, environment and fish health and highlights skin mucus as a valuable minimally invasive biomarker. It is also important to note that improved fish welfare supports fish growth and health and promotes more sustainable aquaculture practices, contributing to more efficient and responsible production in the industry.https://www.mdpi.com/2079-7737/14/2/112skin mucuswelfarebioflocred tilapia (<i>Oreochromis</i> sp.)
spellingShingle Hernán Antonio Alzate-Díaz
Laura Fernández-Alacid
Sandra Clemencia Pardo-Carrasco
Biomarkers in Skin Mucus for a Minimally Invasive Approach to Stress in Red Tilapia (<i>Oreochromis</i> sp.) Fry
Biology
skin mucus
welfare
biofloc
red tilapia (<i>Oreochromis</i> sp.)
title Biomarkers in Skin Mucus for a Minimally Invasive Approach to Stress in Red Tilapia (<i>Oreochromis</i> sp.) Fry
title_full Biomarkers in Skin Mucus for a Minimally Invasive Approach to Stress in Red Tilapia (<i>Oreochromis</i> sp.) Fry
title_fullStr Biomarkers in Skin Mucus for a Minimally Invasive Approach to Stress in Red Tilapia (<i>Oreochromis</i> sp.) Fry
title_full_unstemmed Biomarkers in Skin Mucus for a Minimally Invasive Approach to Stress in Red Tilapia (<i>Oreochromis</i> sp.) Fry
title_short Biomarkers in Skin Mucus for a Minimally Invasive Approach to Stress in Red Tilapia (<i>Oreochromis</i> sp.) Fry
title_sort biomarkers in skin mucus for a minimally invasive approach to stress in red tilapia i oreochromis i sp fry
topic skin mucus
welfare
biofloc
red tilapia (<i>Oreochromis</i> sp.)
url https://www.mdpi.com/2079-7737/14/2/112
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