Effects of physical exercise on improving erectile function: a systematic review and meta-analysis of randomized controlled trials
Background: The study aims to determine the effects of physical exercise (PE) on improving erectile function in adult men with erectile dysfunction (ED) and to explore appropriate clinical exercise regimens through subgroup analyses of factors such as exercise intensity and cycles. Methods: We co...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MRE Press
2025-02-01
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| Series: | Journal of Men's Health |
| Subjects: | |
| Online Access: | https://oss.jomh.org/files/article/20250228-500/pdf/JOMH2024052501.pdf |
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| Summary: | Background: The study aims to determine the effects of physical exercise (PE) on improving
erectile function in adult men with erectile dysfunction (ED) and to explore
appropriate clinical exercise regimens through subgroup analyses of factors such
as exercise intensity and cycles. Methods: We conducted a systematic review of articles
describing randomized controlled trials (RCTs), and conducted subgroup analyses
based on demographic and exercise program characteristics. The primary outcome
indicator was the International Index of Erectile Function (IIEF) score, which
was meta-analyzed to determine the combined effect size. Qualitative analysis was
conducted on other relevant indicators. Results: A total of 10 studies were included in
the meta-analysis and 6 in the qualitative analysis. The results of the
meta-analysis indicated a standardized mean difference (SMD) of 0.892 with a 95%
confidence interval of [0.395–1.388], a Hedges’ g of 0.247, and an
I2 of 88.6% (p < 0.01). Subgroup analysis showed that
the SMD effect was greater in the <60 years age group, the 0–3 months exercise
cycle and the low-intensity group, with p < 0.05; no significant
differences were observed in the subgroups according to country, object or
intervention exercise frequency. Conclusions: This study demonstrated that PE significantly
reduces IIEF scores in patients with ED compared with other interventions for the
treatment of ED, especially in ED patients under 60 years of age with chronic
disease state (CDS). Low-intensity with a 0–3 months duration was more effective
in improving erectile function. This effect is not related to the country,
exercise frequency or intervention group with or without combined drug
intervention. These findings have practical value in guiding healthcare
professionals in the selection of selecting clinical exercise prescription
programs. In addition, physical exercise is also beneficial in improving body
mass index, blood pressure and blood sugar. The PROSPERO Registration: CRD42023445949,
http://www.crd.york.ac.uk/PROSPERO. |
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| ISSN: | 1875-6867 1875-6859 |