Cucurbitacin B inhibits HIF-1α and attenuates non-small cell lung cancer via ZFP91

Non-small cell lung cancer (NSCLC) is among the most common types of cancer and contributes significantly to cancer-related mortality worldwide. Although some progress has been made in the treatment of NSCLC, drug resistance, high costs, and significant individual variability continue to be major ob...

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Main Authors: Lei Song, Jing Han, Run Wang, Shen Cao, Yi Tai, Xinyu Wang, Yanjin Zheng, Shufeng Jin, Yiqian Shen, Cai Qin Liu, Yue Xing, Hong Xiang Zuo, Ming Yue Li, Juan Ma, Xuejun Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1607264/full
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