Research progress in pathogenesis of diabetic kidney disease
Diabetic kidney disease(DKD) is a worldwide public health problem, which is the major cause for morbidity and mortality of patients with diabetes, and the main cause for end-stage kidney diseases. Because of the lack of effective treatment, the research on its mechanism has been the focus of clinica...
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| Format: | Article |
| Language: | zho |
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Editorial Department of Journal of Clinical Nephrology
2020-01-01
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| Series: | Linchuang shenzangbing zazhi |
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| Online Access: | http://www.lcszb.com/thesisDetails?columnId=57907916&Fpath=home&index=0 |
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| author | ZHAO Xi WU Jia-li HUANG Zi-yue LI Dong-yun WEI Dan-xia |
| author_facet | ZHAO Xi WU Jia-li HUANG Zi-yue LI Dong-yun WEI Dan-xia |
| author_sort | ZHAO Xi |
| collection | DOAJ |
| description | Diabetic kidney disease(DKD) is a worldwide public health problem, which is the major cause for morbidity and mortality of patients with diabetes, and the main cause for end-stage kidney diseases. Because of the lack of effective treatment, the research on its mechanism has been the focus of clinical studies. The changes of renal hemodynamics, oxidative stress, inflammation and so on are all related to the pathogenesis of DKD, and the related studies point out that metabolic memory and epigenetics play an important role in the progression of DKD. In this review, we will summarize the progress of the pathogenesis of diabetic kidney disease in combination with the latest studies |
| format | Article |
| id | doaj-art-06fcac202c1c4cea94cce0c6a15ab2eb |
| institution | OA Journals |
| issn | 1671-2390 |
| language | zho |
| publishDate | 2020-01-01 |
| publisher | Editorial Department of Journal of Clinical Nephrology |
| record_format | Article |
| series | Linchuang shenzangbing zazhi |
| spelling | doaj-art-06fcac202c1c4cea94cce0c6a15ab2eb2025-08-20T02:16:13ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902020-01-0120778257907916Research progress in pathogenesis of diabetic kidney diseaseZHAO XiWU Jia-liHUANG Zi-yueLI Dong-yunWEI Dan-xiaDiabetic kidney disease(DKD) is a worldwide public health problem, which is the major cause for morbidity and mortality of patients with diabetes, and the main cause for end-stage kidney diseases. Because of the lack of effective treatment, the research on its mechanism has been the focus of clinical studies. The changes of renal hemodynamics, oxidative stress, inflammation and so on are all related to the pathogenesis of DKD, and the related studies point out that metabolic memory and epigenetics play an important role in the progression of DKD. In this review, we will summarize the progress of the pathogenesis of diabetic kidney disease in combination with the latest studieshttp://www.lcszb.com/thesisDetails?columnId=57907916&Fpath=home&index=0Diabetic kidney diseasePathogenesisEpigeneticsOxidative stressApoptosisCytokine |
| spellingShingle | ZHAO Xi WU Jia-li HUANG Zi-yue LI Dong-yun WEI Dan-xia Research progress in pathogenesis of diabetic kidney disease Linchuang shenzangbing zazhi Diabetic kidney disease Pathogenesis Epigenetics Oxidative stress Apoptosis Cytokine |
| title | Research progress in pathogenesis of diabetic kidney disease |
| title_full | Research progress in pathogenesis of diabetic kidney disease |
| title_fullStr | Research progress in pathogenesis of diabetic kidney disease |
| title_full_unstemmed | Research progress in pathogenesis of diabetic kidney disease |
| title_short | Research progress in pathogenesis of diabetic kidney disease |
| title_sort | research progress in pathogenesis of diabetic kidney disease |
| topic | Diabetic kidney disease Pathogenesis Epigenetics Oxidative stress Apoptosis Cytokine |
| url | http://www.lcszb.com/thesisDetails?columnId=57907916&Fpath=home&index=0 |
| work_keys_str_mv | AT zhaoxi researchprogressinpathogenesisofdiabetickidneydisease AT wujiali researchprogressinpathogenesisofdiabetickidneydisease AT huangziyue researchprogressinpathogenesisofdiabetickidneydisease AT lidongyun researchprogressinpathogenesisofdiabetickidneydisease AT weidanxia researchprogressinpathogenesisofdiabetickidneydisease |