Bilateral synchronous salivary gland tumors: report of three cases

Abstract Background Bilateral salivary gland tumors, both benign and malignant and synchronous or metachronous are very rare. Case presentation Here three cases of synchronous bilateral salivary gland tumors are described and discussed. Recognizing the entity is important for diagnostics and treatme...

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Main Authors: Jacqueline E. van der Wal, Mustafa Barre Magan, Lennart Flygare, Karin Nylander
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Diagnostic Pathology
Subjects:
Online Access:https://doi.org/10.1186/s13000-025-01672-9
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author Jacqueline E. van der Wal
Mustafa Barre Magan
Lennart Flygare
Karin Nylander
author_facet Jacqueline E. van der Wal
Mustafa Barre Magan
Lennart Flygare
Karin Nylander
author_sort Jacqueline E. van der Wal
collection DOAJ
description Abstract Background Bilateral salivary gland tumors, both benign and malignant and synchronous or metachronous are very rare. Case presentation Here three cases of synchronous bilateral salivary gland tumors are described and discussed. Recognizing the entity is important for diagnostics and treatment planning. The first patient was a 56-year-old female with a bilateral parotid tumor, a malignant tumor, salivary duct carcinoma on the right side and a benign tumor, pleomorphic adenoma on the left side. The second patient was a 50-year old female with a bilateral benign parotid tumor, a pleomorphic adenoma. The third patient was a 51-year old female with a bilateral malignant tumor, an acinic cell carcinoma. Details on the diagnostic work-up, histopathology and treatment are described and discussed. Conclusions In the case of a unilateral salivary gland tumor, especially of the major glands, the contralateral gland is always included in the clinical and radiological (MRI) head and neck evaluation prior to surgery, to detect or exclude possible bilateral occurrence.
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spelling doaj-art-06fa90830ce24a32953655ef865ec0342025-08-20T02:06:23ZengBMCDiagnostic Pathology1746-15962025-06-012011910.1186/s13000-025-01672-9Bilateral synchronous salivary gland tumors: report of three casesJacqueline E. van der Wal0Mustafa Barre Magan1Lennart Flygare2Karin Nylander3Department of Medical Biosciences/Pathology, Umeå UniversityDepartment of Medical Biosciences/Pathology, Umeå UniversityDepartment of Diagnostics and Intervention, Umeå UniversityDepartment of Medical Biosciences/Pathology, Umeå UniversityAbstract Background Bilateral salivary gland tumors, both benign and malignant and synchronous or metachronous are very rare. Case presentation Here three cases of synchronous bilateral salivary gland tumors are described and discussed. Recognizing the entity is important for diagnostics and treatment planning. The first patient was a 56-year-old female with a bilateral parotid tumor, a malignant tumor, salivary duct carcinoma on the right side and a benign tumor, pleomorphic adenoma on the left side. The second patient was a 50-year old female with a bilateral benign parotid tumor, a pleomorphic adenoma. The third patient was a 51-year old female with a bilateral malignant tumor, an acinic cell carcinoma. Details on the diagnostic work-up, histopathology and treatment are described and discussed. Conclusions In the case of a unilateral salivary gland tumor, especially of the major glands, the contralateral gland is always included in the clinical and radiological (MRI) head and neck evaluation prior to surgery, to detect or exclude possible bilateral occurrence.https://doi.org/10.1186/s13000-025-01672-9Salivary gland tumorPleomorphic adenomaAcinic cell carcinomaSalivary duct carcinoma
spellingShingle Jacqueline E. van der Wal
Mustafa Barre Magan
Lennart Flygare
Karin Nylander
Bilateral synchronous salivary gland tumors: report of three cases
Diagnostic Pathology
Salivary gland tumor
Pleomorphic adenoma
Acinic cell carcinoma
Salivary duct carcinoma
title Bilateral synchronous salivary gland tumors: report of three cases
title_full Bilateral synchronous salivary gland tumors: report of three cases
title_fullStr Bilateral synchronous salivary gland tumors: report of three cases
title_full_unstemmed Bilateral synchronous salivary gland tumors: report of three cases
title_short Bilateral synchronous salivary gland tumors: report of three cases
title_sort bilateral synchronous salivary gland tumors report of three cases
topic Salivary gland tumor
Pleomorphic adenoma
Acinic cell carcinoma
Salivary duct carcinoma
url https://doi.org/10.1186/s13000-025-01672-9
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AT lennartflygare bilateralsynchronoussalivaryglandtumorsreportofthreecases
AT karinnylander bilateralsynchronoussalivaryglandtumorsreportofthreecases