PGRP-S promotes hepatocellular carcinoma progression via MAPK/ERK pathway by interaction with TTC1

Abstract Abnormal expression of PGRP-S plays an important role in the development and progression of hepatocellular carcinoma (HCC), although the mechanism has remained elusive. In this study, we aimed to investigate the biological function and potential mechanism of PGRP-S in HCC. We found that PGR...

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Bibliographic Details
Main Authors: Huifang Zhu, Shuang Feng, Sizhen Lv, Di Zhao, Xuanhe Chang, Shangqian Fan, Xia Wang, Xinlai Qian
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-12160-x
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