Multi-omics analysis of epigenetic dysregulation reveals clinical heterogeneity and evaluates the immunotherapeutic potential of lung adenocarcinoma

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Main Authors: Yuqing Ren, Zaoqu Liu, Yi Yue, Siyuan Weng, Hongxia Jia, Jing Li, Ping Li, Chunya Lu, Xinwei Han, Guojun Zhang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-09-01
Series:Genes and Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304225000509
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author Yuqing Ren
Zaoqu Liu
Yi Yue
Siyuan Weng
Hongxia Jia
Jing Li
Ping Li
Chunya Lu
Xinwei Han
Guojun Zhang
author_facet Yuqing Ren
Zaoqu Liu
Yi Yue
Siyuan Weng
Hongxia Jia
Jing Li
Ping Li
Chunya Lu
Xinwei Han
Guojun Zhang
author_sort Yuqing Ren
collection DOAJ
format Article
id doaj-art-06ef777eb31b43bca4eb9c473ad9c3a3
institution DOAJ
issn 2352-3042
language English
publishDate 2025-09-01
publisher KeAi Communications Co., Ltd.
record_format Article
series Genes and Diseases
spelling doaj-art-06ef777eb31b43bca4eb9c473ad9c3a32025-08-20T02:43:53ZengKeAi Communications Co., Ltd.Genes and Diseases2352-30422025-09-0112510156110.1016/j.gendis.2025.101561Multi-omics analysis of epigenetic dysregulation reveals clinical heterogeneity and evaluates the immunotherapeutic potential of lung adenocarcinomaYuqing Ren0Zaoqu Liu1Yi Yue2Siyuan Weng3Hongxia Jia4Jing Li5Ping Li6Chunya Lu7Xinwei Han8Guojun Zhang9Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, ChinaState Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Department of Pathophysiology, Peking Union Medical College, Beijing 100730, ChinaDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, ChinaDepartment of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, ChinaDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, ChinaDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, ChinaDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, ChinaDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, ChinaDepartment of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China; Corresponding author.Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China; Corresponding author.http://www.sciencedirect.com/science/article/pii/S2352304225000509
spellingShingle Yuqing Ren
Zaoqu Liu
Yi Yue
Siyuan Weng
Hongxia Jia
Jing Li
Ping Li
Chunya Lu
Xinwei Han
Guojun Zhang
Multi-omics analysis of epigenetic dysregulation reveals clinical heterogeneity and evaluates the immunotherapeutic potential of lung adenocarcinoma
Genes and Diseases
title Multi-omics analysis of epigenetic dysregulation reveals clinical heterogeneity and evaluates the immunotherapeutic potential of lung adenocarcinoma
title_full Multi-omics analysis of epigenetic dysregulation reveals clinical heterogeneity and evaluates the immunotherapeutic potential of lung adenocarcinoma
title_fullStr Multi-omics analysis of epigenetic dysregulation reveals clinical heterogeneity and evaluates the immunotherapeutic potential of lung adenocarcinoma
title_full_unstemmed Multi-omics analysis of epigenetic dysregulation reveals clinical heterogeneity and evaluates the immunotherapeutic potential of lung adenocarcinoma
title_short Multi-omics analysis of epigenetic dysregulation reveals clinical heterogeneity and evaluates the immunotherapeutic potential of lung adenocarcinoma
title_sort multi omics analysis of epigenetic dysregulation reveals clinical heterogeneity and evaluates the immunotherapeutic potential of lung adenocarcinoma
url http://www.sciencedirect.com/science/article/pii/S2352304225000509
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