A Rare Case of Malignant Glomus Tumor of the Esophagus

Glomus tumors are rare neoplasms that usually occur on the hands in a subungual location, or sometimes in palms, wrists or soles of the feet. They are described as purple/pink tiny painful lesions with a triad of pain, local point tenderness, and cold hypersensitivity. They are almost always benign,...

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Main Authors: Gurvinder Singh Bali, Douglas J. Hartman, Joel B. Haight, Michael K. Gibson
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2013/287078
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author Gurvinder Singh Bali
Douglas J. Hartman
Joel B. Haight
Michael K. Gibson
author_facet Gurvinder Singh Bali
Douglas J. Hartman
Joel B. Haight
Michael K. Gibson
author_sort Gurvinder Singh Bali
collection DOAJ
description Glomus tumors are rare neoplasms that usually occur on the hands in a subungual location, or sometimes in palms, wrists or soles of the feet. They are described as purple/pink tiny painful lesions with a triad of pain, local point tenderness, and cold hypersensitivity. They are almost always benign, but rare malignant variants have been reported. They have also been reported to be present at unusual locations, like the lung, stomach, or liver. Gastrointestinal glomus tumors are extremely rare tumors and very few cases have been reported in the literature. Most that have been reported were usually benign in nature. A rare esophageal glomangioma, mimicking a papilloma, was reported in 2006. We report a case of glomangiosarcoma (malignant glomus tumor) in a 49-year-old female, who presented with symptoms of dysphagia including some spasm and hoarseness and subjective unintentional weight loss. On endoscopic exam, she was found to have a distal esophageal mass with malignant features. Radiologically, the mass had a size of about 8 cm on the CT scan without evidence of metastases. Pathology and immunostaining of the biopsy showed features resembling a malignant glomus tumor. She underwent an endoscopic and laparoscopic staging of the tumor along with ultrasound. Based on the laparoscopic findings, which were consistent with the preoperative diagnosis, she was scheduled for an esophagectomy. Histopathology and immunophenotypic features of the excised mass were consistent with a diagnosis of malignant glomus tumor.
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spelling doaj-art-06ecac6cadce45718903a2c64ba2a5dc2025-08-20T02:02:51ZengWileyCase Reports in Oncological Medicine2090-67062090-67142013-01-01201310.1155/2013/287078287078A Rare Case of Malignant Glomus Tumor of the EsophagusGurvinder Singh Bali0Douglas J. Hartman1Joel B. Haight2Michael K. Gibson3University Hospitals Case Medical Center, Seidman Cancer Center, Case Western Reserve University, 11100 Euclid Avenue, LKS 5079, Cleveland, OH 44106, USADivision of Anatomic Pathology, Department of Pathology, University of Pittsburgh Medical Center, 200 Lothrop Street A610, Pittsburgh, PA 15213, USAPenn State Hershey Medical Group Colonnade, 32 Colonnade Way, State College, PA 16803, USAUniversity Hospitals Case Medical Center, Seidman Cancer Center, Case Western Reserve University, 11100 Euclid Avenue, LKS 5079, Cleveland, OH 44106, USAGlomus tumors are rare neoplasms that usually occur on the hands in a subungual location, or sometimes in palms, wrists or soles of the feet. They are described as purple/pink tiny painful lesions with a triad of pain, local point tenderness, and cold hypersensitivity. They are almost always benign, but rare malignant variants have been reported. They have also been reported to be present at unusual locations, like the lung, stomach, or liver. Gastrointestinal glomus tumors are extremely rare tumors and very few cases have been reported in the literature. Most that have been reported were usually benign in nature. A rare esophageal glomangioma, mimicking a papilloma, was reported in 2006. We report a case of glomangiosarcoma (malignant glomus tumor) in a 49-year-old female, who presented with symptoms of dysphagia including some spasm and hoarseness and subjective unintentional weight loss. On endoscopic exam, she was found to have a distal esophageal mass with malignant features. Radiologically, the mass had a size of about 8 cm on the CT scan without evidence of metastases. Pathology and immunostaining of the biopsy showed features resembling a malignant glomus tumor. She underwent an endoscopic and laparoscopic staging of the tumor along with ultrasound. Based on the laparoscopic findings, which were consistent with the preoperative diagnosis, she was scheduled for an esophagectomy. Histopathology and immunophenotypic features of the excised mass were consistent with a diagnosis of malignant glomus tumor.http://dx.doi.org/10.1155/2013/287078
spellingShingle Gurvinder Singh Bali
Douglas J. Hartman
Joel B. Haight
Michael K. Gibson
A Rare Case of Malignant Glomus Tumor of the Esophagus
Case Reports in Oncological Medicine
title A Rare Case of Malignant Glomus Tumor of the Esophagus
title_full A Rare Case of Malignant Glomus Tumor of the Esophagus
title_fullStr A Rare Case of Malignant Glomus Tumor of the Esophagus
title_full_unstemmed A Rare Case of Malignant Glomus Tumor of the Esophagus
title_short A Rare Case of Malignant Glomus Tumor of the Esophagus
title_sort rare case of malignant glomus tumor of the esophagus
url http://dx.doi.org/10.1155/2013/287078
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