Prognostic and molecular multi-platform analysis of CALGB 40603 (Alliance) and public triple-negative breast cancer datasets

Prognostic and molecular multi-platform analysis of CALGB 40603 (Alliance) and public triple-negative breast cancer datasets

Abstract Triple-negative breast cancer (TNBC) is an aggressive and heterogeneous disease that remains challenging to target with traditional therapies and to predict risk. We provide a comprehensive characterization of 238 stage II-III TNBC tumors with paired RNA and DNA sequencing data from the CAL...

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Main Authors: Brooke M. Felsheim, Aranzazu Fernandez-Martinez, Cheng Fan, Adam D. Pfefferle, Michele C. Hayward, Katherine A. Hoadley, Naim U. Rashid, Sara M. Tolaney, George Somlo, Lisa A. Carey, William M. Sikov, Charles M. Perou
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-025-00740-z
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