Biology and Application of <i>Chaetomium globosum</i> as a Biocontrol Agent: Current Status and Future Prospects
<i>Chaetomium globosum</i> is a widely distributed fungal species recognized for its ability to produce a range of secondary metabolites. This fungus plays a significant ecological role by degrading organic matter and contributing to nutrient cycling in diverse ecosystems. In recent year...
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2025-07-01
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| author | Shailja Sharma Saurabh Pandey Sourabh Kulshreshtha Mukesh Dubey |
| author_facet | Shailja Sharma Saurabh Pandey Sourabh Kulshreshtha Mukesh Dubey |
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| description | <i>Chaetomium globosum</i> is a widely distributed fungal species recognized for its ability to produce a range of secondary metabolites. This fungus plays a significant ecological role by degrading organic matter and contributing to nutrient cycling in diverse ecosystems. In recent years, <i>C. globosum</i> has attracted considerable scientific interest due to its potential as a biocontrol agent [BCA] against a wide array of diseases in numerous plant species. While the precise mechanisms of <i>C. globosum</i> as a BCA remain poorly understood, interference competition through antibiosis is one of the key mechanisms. Moreover, <i>C. globosum</i> can enhance plant health by promoting nutrient availability, manipulating the rhizosphere microbiome, and inducing plant defense responses. The formulation of <i>C. globosum</i> for agricultural applications has been reported, which can significantly improve stability and efficacy under field conditions. However, despite significant advancements in omics and molecular biology technologies, the biology of <i>C. globosum</i> is understudied. Enhanced research into the genetics and functional genomics of <i>C. globosum</i> could pave the way for its applications in sustainable agriculture. This review summarizes the role of <i>C. globosum</i> as a BCA, focusing on its underlying mechanisms such as genomics and transcriptomics, and the effects of <i>C. globosum</i> application on soil health and the rhizosphere microbiome. |
| format | Article |
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| institution | Kabale University |
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| publishDate | 2025-07-01 |
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| spelling | doaj-art-06e79336216e46d8a27980203e210fa82025-08-20T03:56:46ZengMDPI AGMicroorganisms2076-26072025-07-01137164610.3390/microorganisms13071646Biology and Application of <i>Chaetomium globosum</i> as a Biocontrol Agent: Current Status and Future ProspectsShailja Sharma0Saurabh Pandey1Sourabh Kulshreshtha2Mukesh Dubey3Faculty of Forensic Sciences, Mandsaur University, SH-31, Mhow–Neemuch By-Pass Square, Rewas-Dewda Road, Mandsaur 458001, IndiaMinistry of Ayush, Ayush Bhawan, New Delhi 110023, IndiaFaculty of Applied Sciences and Biotechnology, Shoolini University of Biotechnology and Management Sciences, Solan 173229, IndiaDepartment of Forest Mycology and Plant Pathology, Swedish University of Agricultural Sciences, 75007 Uppsala, Sweden<i>Chaetomium globosum</i> is a widely distributed fungal species recognized for its ability to produce a range of secondary metabolites. This fungus plays a significant ecological role by degrading organic matter and contributing to nutrient cycling in diverse ecosystems. In recent years, <i>C. globosum</i> has attracted considerable scientific interest due to its potential as a biocontrol agent [BCA] against a wide array of diseases in numerous plant species. While the precise mechanisms of <i>C. globosum</i> as a BCA remain poorly understood, interference competition through antibiosis is one of the key mechanisms. Moreover, <i>C. globosum</i> can enhance plant health by promoting nutrient availability, manipulating the rhizosphere microbiome, and inducing plant defense responses. The formulation of <i>C. globosum</i> for agricultural applications has been reported, which can significantly improve stability and efficacy under field conditions. However, despite significant advancements in omics and molecular biology technologies, the biology of <i>C. globosum</i> is understudied. Enhanced research into the genetics and functional genomics of <i>C. globosum</i> could pave the way for its applications in sustainable agriculture. This review summarizes the role of <i>C. globosum</i> as a BCA, focusing on its underlying mechanisms such as genomics and transcriptomics, and the effects of <i>C. globosum</i> application on soil health and the rhizosphere microbiome.https://www.mdpi.com/2076-2607/13/7/1646antibiosismycoparasitisminduced defense responseinterference competitionmicrobiomeplant health promotion |
| spellingShingle | Shailja Sharma Saurabh Pandey Sourabh Kulshreshtha Mukesh Dubey Biology and Application of <i>Chaetomium globosum</i> as a Biocontrol Agent: Current Status and Future Prospects Microorganisms antibiosis mycoparasitism induced defense response interference competition microbiome plant health promotion |
| title | Biology and Application of <i>Chaetomium globosum</i> as a Biocontrol Agent: Current Status and Future Prospects |
| title_full | Biology and Application of <i>Chaetomium globosum</i> as a Biocontrol Agent: Current Status and Future Prospects |
| title_fullStr | Biology and Application of <i>Chaetomium globosum</i> as a Biocontrol Agent: Current Status and Future Prospects |
| title_full_unstemmed | Biology and Application of <i>Chaetomium globosum</i> as a Biocontrol Agent: Current Status and Future Prospects |
| title_short | Biology and Application of <i>Chaetomium globosum</i> as a Biocontrol Agent: Current Status and Future Prospects |
| title_sort | biology and application of i chaetomium globosum i as a biocontrol agent current status and future prospects |
| topic | antibiosis mycoparasitism induced defense response interference competition microbiome plant health promotion |
| url | https://www.mdpi.com/2076-2607/13/7/1646 |
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