Aclysiran, an RNAi therapeutic agent targeting ACLY, treats hypercholesterolemia and atherosclerosis in ApoE–/– mice
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| Format: | Article |
| Language: | English |
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Elsevier
2024-12-01
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| Series: | Acta Pharmaceutica Sinica B |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211383524004088 |
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| author | Meijie Chen Peter J. Little Sudong Kong Maciej Banach Jianping Weng Suowen Xu |
| author_facet | Meijie Chen Peter J. Little Sudong Kong Maciej Banach Jianping Weng Suowen Xu |
| author_sort | Meijie Chen |
| collection | DOAJ |
| format | Article |
| id | doaj-art-06de8c1c6b60458b85e2a043b4eb1ba4 |
| institution | OA Journals |
| issn | 2211-3835 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Acta Pharmaceutica Sinica B |
| spelling | doaj-art-06de8c1c6b60458b85e2a043b4eb1ba42025-08-20T02:37:04ZengElsevierActa Pharmaceutica Sinica B2211-38352024-12-0114125505550810.1016/j.apsb.2024.10.008Aclysiran, an RNAi therapeutic agent targeting ACLY, treats hypercholesterolemia and atherosclerosis in ApoE–/– miceMeijie Chen0Peter J. Little1Sudong Kong2Maciej Banach3Jianping Weng4Suowen Xu5Department of Endocrinology, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China; Anhui Provincial Key Laboratory of Metabolic Health and Panvascular Diseases, Hefei 230001, ChinaDepartment of Pharmacy, Guangzhou Xinhua University, Guangzhou 510520, ChinaSuzhou Biosyntech Co., Ltd., Suzhou 215300, ChinaDepartment of Preventive Cardiology and Lipidology, Medical University of Lodz 23 (MUL), Lodz 93-338, Poland; Corresponding authors.Department of Endocrinology, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China; Anhui Provincial Key Laboratory of Metabolic Health and Panvascular Diseases, Hefei 230001, China; Corresponding authors.Department of Endocrinology, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China; Anhui Provincial Key Laboratory of Metabolic Health and Panvascular Diseases, Hefei 230001, China; Corresponding authors.http://www.sciencedirect.com/science/article/pii/S2211383524004088AclysiranACLYAtherosclerosis |
| spellingShingle | Meijie Chen Peter J. Little Sudong Kong Maciej Banach Jianping Weng Suowen Xu Aclysiran, an RNAi therapeutic agent targeting ACLY, treats hypercholesterolemia and atherosclerosis in ApoE–/– mice Acta Pharmaceutica Sinica B Aclysiran ACLY Atherosclerosis |
| title | Aclysiran, an RNAi therapeutic agent targeting ACLY, treats hypercholesterolemia and atherosclerosis in ApoE–/– mice |
| title_full | Aclysiran, an RNAi therapeutic agent targeting ACLY, treats hypercholesterolemia and atherosclerosis in ApoE–/– mice |
| title_fullStr | Aclysiran, an RNAi therapeutic agent targeting ACLY, treats hypercholesterolemia and atherosclerosis in ApoE–/– mice |
| title_full_unstemmed | Aclysiran, an RNAi therapeutic agent targeting ACLY, treats hypercholesterolemia and atherosclerosis in ApoE–/– mice |
| title_short | Aclysiran, an RNAi therapeutic agent targeting ACLY, treats hypercholesterolemia and atherosclerosis in ApoE–/– mice |
| title_sort | aclysiran an rnai therapeutic agent targeting acly treats hypercholesterolemia and atherosclerosis in apoe mice |
| topic | Aclysiran ACLY Atherosclerosis |
| url | http://www.sciencedirect.com/science/article/pii/S2211383524004088 |
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