Effect of Topical Atropine on Wound Contraction in Swiss Albino Mice : A preliminary report

The influence of topical application of atropine ointment was studied in artificially wounded Swiss albino mice. Full thickness excision wounds were made surgically on the dorsum of mice. One mm thick layer of atropine ointment was applied topically on the whole area of wound daily, till the healing...

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Main Authors: P Kumar, G C Jagetia
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2000-02-01
Series:Indian Journal of Plastic Surgery
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1778539
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author P Kumar
G C Jagetia
author_facet P Kumar
G C Jagetia
author_sort P Kumar
collection DOAJ
description The influence of topical application of atropine ointment was studied in artificially wounded Swiss albino mice. Full thickness excision wounds were made surgically on the dorsum of mice. One mm thick layer of atropine ointment was applied topically on the whole area of wound daily, till the healing of wound. The topical application of atropine ointment significantly delayed the contraction of wound in the atropine treated group when compared with the untreated controls. There was a significant delay in the mean wound healing time (HTM) in the atropine treated group when compared to untreated control group.
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institution OA Journals
issn 0970-0358
1998-376X
language English
publishDate 2000-02-01
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
record_format Article
series Indian Journal of Plastic Surgery
spelling doaj-art-06d73873efc84c0599c8b9aa7688690f2025-08-20T02:02:51ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Plastic Surgery0970-03581998-376X2000-02-01330208608910.1055/s-0043-1778539Effect of Topical Atropine on Wound Contraction in Swiss Albino Mice : A preliminary reportP Kumar0G C Jagetia1Department of Plastic Surgery, Kasturba Medical CollegeDepartment of Radiobiology, Kastruba Medical College, Manipal 576 119, Kamataka, IndiaThe influence of topical application of atropine ointment was studied in artificially wounded Swiss albino mice. Full thickness excision wounds were made surgically on the dorsum of mice. One mm thick layer of atropine ointment was applied topically on the whole area of wound daily, till the healing of wound. The topical application of atropine ointment significantly delayed the contraction of wound in the atropine treated group when compared with the untreated controls. There was a significant delay in the mean wound healing time (HTM) in the atropine treated group when compared to untreated control group.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1778539
spellingShingle P Kumar
G C Jagetia
Effect of Topical Atropine on Wound Contraction in Swiss Albino Mice : A preliminary report
Indian Journal of Plastic Surgery
title Effect of Topical Atropine on Wound Contraction in Swiss Albino Mice : A preliminary report
title_full Effect of Topical Atropine on Wound Contraction in Swiss Albino Mice : A preliminary report
title_fullStr Effect of Topical Atropine on Wound Contraction in Swiss Albino Mice : A preliminary report
title_full_unstemmed Effect of Topical Atropine on Wound Contraction in Swiss Albino Mice : A preliminary report
title_short Effect of Topical Atropine on Wound Contraction in Swiss Albino Mice : A preliminary report
title_sort effect of topical atropine on wound contraction in swiss albino mice a preliminary report
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1778539
work_keys_str_mv AT pkumar effectoftopicalatropineonwoundcontractioninswissalbinomiceapreliminaryreport
AT gcjagetia effectoftopicalatropineonwoundcontractioninswissalbinomiceapreliminaryreport