Injectable hyaluronate-L- cysteine gel potentiates photothermal therapy in osteosarcoma via vorinostat-copper cell death

Injectable hyaluronate-L- cysteine gel potentiates photothermal therapy in osteosarcoma via vorinostat-copper cell death

The prognosis for osteosarcoma patients, a devastating malignancy affecting young individuals, remains grim despite multimodal therapeutic advances. Recently, the advent of cuproptosis, a novel programmed cell death, offers hope in fighting osteosarcoma. In this study, we introduce SAHAm@{[Cu(HA-Cys...

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Bibliographic Details
Main Authors: Sizhen Wang, Hanzhe Zhang, Tianheng Chen, Weiwei Jiang, Feng Wang, Yuhao Yu, Beibei Guo, Jia Xu, Feng Yang, Qinglin Kang, Zhiqiang Ma
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Materials Today Bio
Subjects:
Cuproptosis
Osteosarcoma
Injectable hydrogel
Phototherapy
Vorinostat
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424004290
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