Deciphering ferroptosis in critical care: mechanisms, consequences, and therapeutic opportunities

Deciphering ferroptosis in critical care: mechanisms, consequences, and therapeutic opportunities

Ischemia-reperfusion injuries (IRI) across various organs and tissues, along with sepsis, significantly contribute to the progression of critical illnesses. These conditions disrupt the balance of inflammatory mediators and signaling pathways, resulting in impaired physiological functions in human t...

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Bibliographic Details
Main Authors: Ruimin Tan, Chen Ge, Yating Yan, He Guo, Xumin Han, Qiong Zhu, Quansheng Du
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
ferroptosis
critical illness
iron overload
lipid metabolism
mitochondrial dysfunction
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1511015/full
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