AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS
Abstract. A new method of enzyme-linked immunosorbent assay (in solid-phase ELISA format) has been developed to determine concentrations of autoantibodies to glutamic acid decarboxylase, as well as an evidencebased methodology is proposed for its medical implications, as a quantitative pathogenetic...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2014-07-01
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| Series: | Медицинская иммунология |
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| Online Access: | https://www.mimmun.ru/mimmun/article/view/511 |
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| author | N. V. Piven L. N. Lukhverchyk A. I. Burakovsky N. V. Polegenkaya M. V. Karpovich |
| author_facet | N. V. Piven L. N. Lukhverchyk A. I. Burakovsky N. V. Polegenkaya M. V. Karpovich |
| author_sort | N. V. Piven |
| collection | DOAJ |
| description | Abstract. A new method of enzyme-linked immunosorbent assay (in solid-phase ELISA format) has been developed to determine concentrations of autoantibodies to glutamic acid decarboxylase, as well as an evidencebased methodology is proposed for its medical implications, as a quantitative pathogenetic predictive marker of autoimmune diagnostics in type 1 diabetes mellitus. This technique could be implied for serial production of diagnostic reagent kits, aimed for detection of autoantibodies to glutamic acid decarboxylase by means of ELISA approach. (Med. Immunol., 2011, vol. 13, N 2-3, pp 257-260) |
| format | Article |
| id | doaj-art-06cf4f3946f64cc3b21d9c52a17c2f71 |
| institution | Kabale University |
| issn | 1563-0625 2313-741X |
| language | Russian |
| publishDate | 2014-07-01 |
| publisher | St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists |
| record_format | Article |
| series | Медицинская иммунология |
| spelling | doaj-art-06cf4f3946f64cc3b21d9c52a17c2f712025-08-20T03:37:46ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-07-01132-325726010.15789/1563-0625-2011-2-3-257-260508AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUSN. V. Piven0L. N. Lukhverchyk1A. I. Burakovsky2N. V. Polegenkaya3M. V. Karpovich4ГНУ «Институт биоорганической химии НАН Беларуси», г. МинскГНУ «Институт биоорганической химии НАН Беларуси», г. МинскГНУ «Институт биоорганической химии НАН Беларуси», г. МинскГНУ «Институт биоорганической химии НАН Беларуси», г. МинскГНУ «Институт биоорганической химии НАН Беларуси», г. МинскAbstract. A new method of enzyme-linked immunosorbent assay (in solid-phase ELISA format) has been developed to determine concentrations of autoantibodies to glutamic acid decarboxylase, as well as an evidencebased methodology is proposed for its medical implications, as a quantitative pathogenetic predictive marker of autoimmune diagnostics in type 1 diabetes mellitus. This technique could be implied for serial production of diagnostic reagent kits, aimed for detection of autoantibodies to glutamic acid decarboxylase by means of ELISA approach. (Med. Immunol., 2011, vol. 13, N 2-3, pp 257-260)https://www.mimmun.ru/mimmun/article/view/511autoantibodiesglutamic acid decarboxylaseimmunoenzyme assaydiabetes mellituspathogenesis |
| spellingShingle | N. V. Piven L. N. Lukhverchyk A. I. Burakovsky N. V. Polegenkaya M. V. Karpovich AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS Медицинская иммунология autoantibodies glutamic acid decarboxylase immunoenzyme assay diabetes mellitus pathogenesis |
| title | AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS |
| title_full | AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS |
| title_fullStr | AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS |
| title_full_unstemmed | AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS |
| title_short | AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS |
| title_sort | autoantibodies to glutamic acid decarboxylase as a pathogenetic marker of type i diabetes mellitus |
| topic | autoantibodies glutamic acid decarboxylase immunoenzyme assay diabetes mellitus pathogenesis |
| url | https://www.mimmun.ru/mimmun/article/view/511 |
| work_keys_str_mv | AT nvpiven autoantibodiestoglutamicaciddecarboxylaseasapathogeneticmarkeroftypeidiabetesmellitus AT lnlukhverchyk autoantibodiestoglutamicaciddecarboxylaseasapathogeneticmarkeroftypeidiabetesmellitus AT aiburakovsky autoantibodiestoglutamicaciddecarboxylaseasapathogeneticmarkeroftypeidiabetesmellitus AT nvpolegenkaya autoantibodiestoglutamicaciddecarboxylaseasapathogeneticmarkeroftypeidiabetesmellitus AT mvkarpovich autoantibodiestoglutamicaciddecarboxylaseasapathogeneticmarkeroftypeidiabetesmellitus |