Atrial remodelling and dysfunction in hypertrophic cardiomyopathy: prognostic role and therapeutic target

Atrial remodelling and dysfunction in hypertrophic cardiomyopathy: prognostic role and therapeutic target

IntroductionHypertrophic cardiomyopathy (HCM) is a common genetic cardiac disease marked by abnormal ventricular hypertrophy. Recent studies have highlighted that left atrial (LA) remodelling—including dilation, fibrosis, and functional impairment—plays a key role in disease progression and prognosi...

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Main Authors: Chiara Piazzai, Alessio Petrone, Andrea Stefanini, Flavio D’Ascenzi, Iacopo Olivotto, Matteo Cameli
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
hypertrophic cardiomyopathy
atrial myopathy
multimodal imaging
atrial fibrillation
septal reduction therapy
cardiac myosin inhibitors
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1620313/full
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