The Cytotoxic Role of Intermittent High Glucose on Apoptosis and Cell Viability in Pancreatic Beta Cells

The Cytotoxic Role of Intermittent High Glucose on Apoptosis and Cell Viability in Pancreatic Beta Cells

Objectives. Glucose fluctuations are both strong predictor of diabetic complications and crucial factor for beta cell damages. Here we investigated the effect of intermittent high glucose (IHG) on both cell apoptosis and proliferation activity in INS-1 cells and the potential mechanisms. Methods. Ce...

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Bibliographic Details
Main Authors:	Zhen Zhang, Jing Li, Lei Yang, Rongping Chen, Rui Yang, Hua Zhang, Dehong Cai, Hong Chen
Format:	Article
Language:	English
Published:	Wiley 2014-01-01
Series:	Journal of Diabetes Research
Online Access:	http://dx.doi.org/10.1155/2014/712781
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