A Novel Electrocardiographic Marker to Predict the Development of Preeclampsia: Frontal QRS-T Angle—A Prospective Pilot Study
<i>Background and Objectives</i>: Preeclampsia, a pregnancy-induced hypertensive disorder, shares cardiovascular characteristics in etiology, prognosis, and fetomaternal risks. Electrocardiography plays a pivotal role in assessing cardiovascular risks. Beyond conventional predictors, ide...
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MDPI AG
2024-11-01
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| author | Elif Uçar Kenan Toprak Mesut Karataş |
| author_facet | Elif Uçar Kenan Toprak Mesut Karataş |
| author_sort | Elif Uçar |
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| description | <i>Background and Objectives</i>: Preeclampsia, a pregnancy-induced hypertensive disorder, shares cardiovascular characteristics in etiology, prognosis, and fetomaternal risks. Electrocardiography plays a pivotal role in assessing cardiovascular risks. Beyond conventional predictors, identifying easily obtainable and reproducible electrocardiographic markers may significantly contribute to the early identification of individuals at risk of preeclampsia. In this study, we aimed to investigate the value of the Frontal QRS-T angle and other electrocardiographic parameters in predicting the development of preeclampsia. <i>Materials and Methods</i>: A total of 62 pregnant patients diagnosed with preeclampsia and 50 healthy pregnant patients as the control group were included in this study. The first- and third-trimester electrocardiographic parameters were compared within groups and between groups. <i>Results</i>: The Frontal QRS-T angle was significantly elevated in patients with preeclampsia compared to the controls (55.0 ± 40.8 vs. 19.5 ± 15.1; <i>p</i> = 0.002). The first-trimester Frontal QRS-T angles in the patients with preeclampsia were higher than those of the controls (29.5 ± 25.0 vs. 15.3 ± 11.5; <i>p</i> = 0.015). A high Frontal QRS-T angle independently marked preeclampsia development in antenatal and late pregnancy (<i>p</i> = 0.003 and <i>p</i> = 0.042, respectively). The diagnostic accuracy of the Frontal QRS-T angle in predicting preeclampsia surpassed other electrocardiographic parameters. <i>Conclusions</i>: This study shows that the Frontal QRS-T angle may be a candidate to be an independent predictor for the development of preeclampsia. In this context, the Frontal QRS-T angle, which is an electrocardiographic parameter, seems promising. |
| format | Article |
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| language | English |
| publishDate | 2024-11-01 |
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| series | Medicina |
| spelling | doaj-art-06babbd12d754dc4aa2c801804caf9aa2025-08-20T02:05:04ZengMDPI AGMedicina1010-660X1648-91442024-11-016011185610.3390/medicina60111856A Novel Electrocardiographic Marker to Predict the Development of Preeclampsia: Frontal QRS-T Angle—A Prospective Pilot StudyElif Uçar0Kenan Toprak1Mesut Karataş2Department of Gynecology and Obstetric, Private Esencan Hospital, Istanbul Esenyurt University, 63050 Istanbul, TurkeyDepartment of Cardiology, Faculty of Medicine, Harran University, Viranşehir Road, Osmanbey Campus, 63300 Sanliurfa, TurkeyKartal Koşuyolu High Specialization Training and Research Hospital, 63050 Istanbul, Turkey<i>Background and Objectives</i>: Preeclampsia, a pregnancy-induced hypertensive disorder, shares cardiovascular characteristics in etiology, prognosis, and fetomaternal risks. Electrocardiography plays a pivotal role in assessing cardiovascular risks. Beyond conventional predictors, identifying easily obtainable and reproducible electrocardiographic markers may significantly contribute to the early identification of individuals at risk of preeclampsia. In this study, we aimed to investigate the value of the Frontal QRS-T angle and other electrocardiographic parameters in predicting the development of preeclampsia. <i>Materials and Methods</i>: A total of 62 pregnant patients diagnosed with preeclampsia and 50 healthy pregnant patients as the control group were included in this study. The first- and third-trimester electrocardiographic parameters were compared within groups and between groups. <i>Results</i>: The Frontal QRS-T angle was significantly elevated in patients with preeclampsia compared to the controls (55.0 ± 40.8 vs. 19.5 ± 15.1; <i>p</i> = 0.002). The first-trimester Frontal QRS-T angles in the patients with preeclampsia were higher than those of the controls (29.5 ± 25.0 vs. 15.3 ± 11.5; <i>p</i> = 0.015). A high Frontal QRS-T angle independently marked preeclampsia development in antenatal and late pregnancy (<i>p</i> = 0.003 and <i>p</i> = 0.042, respectively). The diagnostic accuracy of the Frontal QRS-T angle in predicting preeclampsia surpassed other electrocardiographic parameters. <i>Conclusions</i>: This study shows that the Frontal QRS-T angle may be a candidate to be an independent predictor for the development of preeclampsia. In this context, the Frontal QRS-T angle, which is an electrocardiographic parameter, seems promising.https://www.mdpi.com/1648-9144/60/11/1856electrocardiographyFrontal QRS-T anglepreeclampsia |
| spellingShingle | Elif Uçar Kenan Toprak Mesut Karataş A Novel Electrocardiographic Marker to Predict the Development of Preeclampsia: Frontal QRS-T Angle—A Prospective Pilot Study Medicina electrocardiography Frontal QRS-T angle preeclampsia |
| title | A Novel Electrocardiographic Marker to Predict the Development of Preeclampsia: Frontal QRS-T Angle—A Prospective Pilot Study |
| title_full | A Novel Electrocardiographic Marker to Predict the Development of Preeclampsia: Frontal QRS-T Angle—A Prospective Pilot Study |
| title_fullStr | A Novel Electrocardiographic Marker to Predict the Development of Preeclampsia: Frontal QRS-T Angle—A Prospective Pilot Study |
| title_full_unstemmed | A Novel Electrocardiographic Marker to Predict the Development of Preeclampsia: Frontal QRS-T Angle—A Prospective Pilot Study |
| title_short | A Novel Electrocardiographic Marker to Predict the Development of Preeclampsia: Frontal QRS-T Angle—A Prospective Pilot Study |
| title_sort | novel electrocardiographic marker to predict the development of preeclampsia frontal qrs t angle a prospective pilot study |
| topic | electrocardiography Frontal QRS-T angle preeclampsia |
| url | https://www.mdpi.com/1648-9144/60/11/1856 |
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