Probing the HIV-1 genomic RNA trafficking pathway and dimerization by genetic recombination and single virion analyses.
Once transcribed, the nascent full-length RNA of HIV-1 must travel to the appropriate host cell sites to be translated or to find a partner RNA for copackaging to form newly generated viruses. In this report, we sought to delineate the location where HIV-1 RNA initiates dimerization and the influenc...
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| Main Authors: | Michael D Moore, Olga A Nikolaitchik, Jianbo Chen, Marie-Louise Hammarskjöld, David Rekosh, Wei-Shau Hu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-10-01
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| Series: | PLoS Pathogens |
| Online Access: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1000627&type=printable |
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