Hypoxia‐Driven Neurovascular Impairment Underlies Structural‐Functional Dissociation in Diabetic Sudomotor Dysfunction

Hypoxia‐Driven Neurovascular Impairment Underlies Structural‐Functional Dissociation in Diabetic Sudomotor Dysfunction

ABSTRACT Sudomotor dysfunction in diabetic patients increases the risk of fissures, infections, and diabetic foot ulcers (DFUs), thereby reducing the quality of life. Despite its clinical importance, the mechanisms underlying this dysfunction remain inadequately elucidated. This study addresses this...

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Main Authors: Xu Guo, Chao Zhang, Yuzhen Wang, Zhao Li, Yaxin Tan, Dongzhen Zhu, Wei Song, Yi Kong, Jinpeng Du, Yuyan Huang, Liting Liang, Jianjun Li, Mengde Zhang, Linhao Hou, Qinhua Liu, Feng Tian, Bingyang Yu, Yue Kong, Zhenyu Zhou, Xiaobing Fu, Sha Huang
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:MedComm
Subjects:
neural support
neurovascular network
sudomotor dysfunction
sweat gland cell–neural cell interaction model
sweat gland microenvironment
Online Access:https://doi.org/10.1002/mco2.70173
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https://doi.org/10.1002/mco2.70173

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