Malignant Peripheral Nerve Sheath Tumor: MRI and CT Findings
This is a case report of a 56-year-old male with hypertension who presented with urinary retention and bowel incontinence. CT and MRI of the abdomen and pelvis showed a large complex cystic and solid enhancing mass in the right presacral space. Pathology biopsy result showed malignant peripheral ner...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Radiology |
| Online Access: | http://dx.doi.org/10.1155/2015/241259 |
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| author | K. O. Kragha |
| author_facet | K. O. Kragha |
| author_sort | K. O. Kragha |
| collection | DOAJ |
| description | This is a case report of a 56-year-old male with hypertension who presented with urinary retention and bowel incontinence. CT and MRI of the abdomen and pelvis showed a large complex cystic and solid enhancing mass in the right presacral space. Pathology biopsy result showed malignant peripheral nerve sheath tumor (MPNST) with extensive necrosis. The diagnosis of MPNST is extremely difficult due to the lack of (1) conclusive immunohistochemistry or unique chromosomal anomaly, (2) universal distinctive histopathology, and (3) clinical criteria. The clinical, radiologic, and histologic presentation of MPNST is
important in its diagnosis. A rare case of MPNST that produced urinary retention and bowel incontinence is presented that may aid clinicians in the diagnosis of this rare clinical entity. Motor weakness, central enhancement, and immunohistochemistry may assist in the diagnosis of MPNST and differentiation between benign peripheral nerve sheath tumor (BPNST) and MPNST. |
| format | Article |
| id | doaj-art-06b206c3627f42cb859630ab13124726 |
| institution | Kabale University |
| issn | 2090-6862 2090-6870 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Radiology |
| spelling | doaj-art-06b206c3627f42cb859630ab131247262025-02-03T05:44:00ZengWileyCase Reports in Radiology2090-68622090-68702015-01-01201510.1155/2015/241259241259Malignant Peripheral Nerve Sheath Tumor: MRI and CT FindingsK. O. Kragha0Department of Radiology, University of Louisville, 530 S. S. Jackson Street, CCB C07, Louisville, KY 40202, USAThis is a case report of a 56-year-old male with hypertension who presented with urinary retention and bowel incontinence. CT and MRI of the abdomen and pelvis showed a large complex cystic and solid enhancing mass in the right presacral space. Pathology biopsy result showed malignant peripheral nerve sheath tumor (MPNST) with extensive necrosis. The diagnosis of MPNST is extremely difficult due to the lack of (1) conclusive immunohistochemistry or unique chromosomal anomaly, (2) universal distinctive histopathology, and (3) clinical criteria. The clinical, radiologic, and histologic presentation of MPNST is important in its diagnosis. A rare case of MPNST that produced urinary retention and bowel incontinence is presented that may aid clinicians in the diagnosis of this rare clinical entity. Motor weakness, central enhancement, and immunohistochemistry may assist in the diagnosis of MPNST and differentiation between benign peripheral nerve sheath tumor (BPNST) and MPNST.http://dx.doi.org/10.1155/2015/241259 |
| spellingShingle | K. O. Kragha Malignant Peripheral Nerve Sheath Tumor: MRI and CT Findings Case Reports in Radiology |
| title | Malignant Peripheral Nerve Sheath Tumor: MRI and CT Findings |
| title_full | Malignant Peripheral Nerve Sheath Tumor: MRI and CT Findings |
| title_fullStr | Malignant Peripheral Nerve Sheath Tumor: MRI and CT Findings |
| title_full_unstemmed | Malignant Peripheral Nerve Sheath Tumor: MRI and CT Findings |
| title_short | Malignant Peripheral Nerve Sheath Tumor: MRI and CT Findings |
| title_sort | malignant peripheral nerve sheath tumor mri and ct findings |
| url | http://dx.doi.org/10.1155/2015/241259 |
| work_keys_str_mv | AT kokragha malignantperipheralnervesheathtumormriandctfindings |