Both TLR2 and TRIF contribute to interferon-β production during Listeria infection.

Both TLR2 and TRIF contribute to interferon-β production during Listeria infection.

Synthesis of interferon-β (IFN-β) is an innate response to cytoplasmic infection with bacterial pathogens. Our recent studies showed that Listeria monocytogenes limits immune detection and IFN-β synthesis via deacetylation of its peptidoglycan, which renders the bacterium resistant to lysozyme degra...

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Bibliographic Details
Main Authors: Camille Aubry, Sinéad C Corr, Sebastian Wienerroither, Céline Goulard, Ruth Jones, Amanda M Jamieson, Thomas Decker, Luke A J O'Neill, Olivier Dussurget, Pascale Cossart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0033299
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