Congenital acute megakaryocytic leukemia
Congenital leukemia (CL) is an extremely rare disorder in the newborn, significant proportion of which is of myeloid origin, primarily of M4 or M5 morphology. As compared to pediatric leukemia, CL is a more aggressive disease. Acute myeloid leukemia (AML-M7) or acute megakaryocytic leukemia is a rar...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2011-01-01
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| Series: | Indian Journal of Medical and Paediatric Oncology |
| Subjects: | |
| Online Access: | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2011;volume=32;issue=3;spage=165;epage=167;aulast=Mathur |
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| _version_ | 1849760879216689152 |
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| author | N B Mathur Neha Joshi T Singh Meeta Singh |
| author_facet | N B Mathur Neha Joshi T Singh Meeta Singh |
| author_sort | N B Mathur |
| collection | DOAJ |
| description | Congenital leukemia (CL) is an extremely rare disorder in the newborn, significant proportion of which is of myeloid origin, primarily of M4 or M5 morphology. As compared to pediatric leukemia, CL is a more aggressive disease. Acute myeloid leukemia (AML-M7) or acute megakaryocytic leukemia is a rare type of AML with an incidence of 0.5 per million per year. Median age of presentation is 6 years, and children may present with a broad variety of symptoms including low-grade fever, diarrhea, easy bruising, failure to gain weight and life-threatening conditions. |
| format | Article |
| id | doaj-art-06a05dd2d8fe44e3aaf7d1516d8327bc |
| institution | DOAJ |
| issn | 0971-5851 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Medical and Paediatric Oncology |
| spelling | doaj-art-06a05dd2d8fe44e3aaf7d1516d8327bc2025-08-20T03:06:12ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58512011-01-0132316516710.4103/0971-5851.92821Congenital acute megakaryocytic leukemiaN B MathurNeha JoshiT SinghMeeta SinghCongenital leukemia (CL) is an extremely rare disorder in the newborn, significant proportion of which is of myeloid origin, primarily of M4 or M5 morphology. As compared to pediatric leukemia, CL is a more aggressive disease. Acute myeloid leukemia (AML-M7) or acute megakaryocytic leukemia is a rare type of AML with an incidence of 0.5 per million per year. Median age of presentation is 6 years, and children may present with a broad variety of symptoms including low-grade fever, diarrhea, easy bruising, failure to gain weight and life-threatening conditions.http://www.ijmpo.org/article.asp?issn=0971-5851;year=2011;volume=32;issue=3;spage=165;epage=167;aulast=MathurCongenital megakaryocytic leukemianeonatesepsis |
| spellingShingle | N B Mathur Neha Joshi T Singh Meeta Singh Congenital acute megakaryocytic leukemia Indian Journal of Medical and Paediatric Oncology Congenital megakaryocytic leukemia neonate sepsis |
| title | Congenital acute megakaryocytic leukemia |
| title_full | Congenital acute megakaryocytic leukemia |
| title_fullStr | Congenital acute megakaryocytic leukemia |
| title_full_unstemmed | Congenital acute megakaryocytic leukemia |
| title_short | Congenital acute megakaryocytic leukemia |
| title_sort | congenital acute megakaryocytic leukemia |
| topic | Congenital megakaryocytic leukemia neonate sepsis |
| url | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2011;volume=32;issue=3;spage=165;epage=167;aulast=Mathur |
| work_keys_str_mv | AT nbmathur congenitalacutemegakaryocyticleukemia AT nehajoshi congenitalacutemegakaryocyticleukemia AT tsingh congenitalacutemegakaryocyticleukemia AT meetasingh congenitalacutemegakaryocyticleukemia |