Mettl3 deficiency leads to impaired insulin secretion via regulating Ire1a of mature β-cells in mice

Abstract The modification of N6-methyladenosine (m6A) influences the translation and stability of transcripts, allowing for the coordination of gene regulation during cell state maintenance and transition. Deregulation of components in the m6A regulatory network is associated with glucose homeostasi...

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Bibliographic Details
Main Authors: Xu Zhang, Aijing Shan, Jie Chen, Yanan Cao, Xiuli Jiang
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-93799-4
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